ENSMUSG00000031552


Mus musculus

Features
Gene ID: ENSMUSG00000031552
  
Biological name :Adam18
  
Synonyms : Adam18 / Disintegrin and metalloproteinase domain-containing protein 18 / Q9R157
  
Possible biological names infered from orthology : ADAM metallopeptidase domain 18 / Q9Y3Q7
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: A2
Gene start: 24602246
Gene end: 24674755
  
Corresponding Affymetrix probe sets: 10577666 (MoGene1.0st)   1419726_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000133378
Ensembl peptide - ENSMUSP00000148259
Ensembl peptide - ENSMUSP00000033957
NCBI entrez gene - 13524     See in Manteia.
MGI - MGI:105986
RefSeq - NM_010084
RefSeq Peptide - NP_034214
swissprot - Q9R157
swissprot - A0A1B0GT98
swissprot - G3UWP9
Ensembl - ENSMUSG00000031552
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:174164ENSDARG00000057138Danio rerio
 ENSGALG00000044168Gallus gallus
 ENSGALG00000044866Gallus gallus
 ADAM18ENSG00000168619Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Adam3 / F8VQ03 / A disintegrin and metallopeptidase domain 3 ENSMUSG0000003155339
Adam32 / Q8K410 / Disintegrin and metalloproteinase domain-containing protein 32 / Q8TC27* / ADAM metallopeptidase domain 32*ENSMUSG0000003743738
Adam2 / Q60718 / Disintegrin and metalloproteinase domain-containing protein 2 / Q99965* / ADAM metallopeptidase domain 2*ENSMUSG0000002203938
Adam5 / Q3TTE0 / Disintegrin and metalloproteinase domain-containing protein 5 ENSMUSG0000003155437
Adam9 / Q61072 / Disintegrin and metalloproteinase domain-containing protein 9 / Q13443* / ADAM metallopeptidase domain 9*ENSMUSG0000003155530
Adam1b / Q8R534 / Disintegrin and metalloproteinase domain-containing protein 1b ENSMUSG0000006243827
Adam1a / O54992 / Q60813 / Disintegrin and metalloproteinase domain-containing protein 1a ENSMUSG0000007264727
Adam21 / Q9JI76 / Disintegrin and metalloproteinase domain-containing protein 21 / Q9UKJ8* / ADAM metallopeptidase domain 21*ENSMUSG0000000843826
Adam30 / a disintegrin and metallopeptidase domain 30 / Q9UKF2* / ADAM metallopeptidase domain 30*ENSMUSG0000004346826
Adam39 / a disintegrin and metallopeptidase domain 39ENSMUSG0000005403326
Q9R158 / Adam26a / Disintegrin and metalloproteinase domain-containing protein 26A ENSMUSG0000004851625
Adam25ENSMUSG0000007193725
Adam26b / a disintegrin and metallopeptidase domain 26BENSMUSG0000006390025
Adam24 / Q9R160 / Disintegrin and metalloproteinase domain-containing protein 24 ENSMUSG0000004672325
Adam34 / a disintegrin and metallopeptidase domain 34ENSMUSG0000007905825
Adam20 / a disintegrin and metallopeptidase domain 20ENSMUSG0000004628225
Gm5346ENSMUSG0000005019025
Adam6b / a disintegrin and metallopeptidase domain 6BENSMUSG0000005180424
Adam6a / a disintegrin and metallopeptidase domain 6AENSMUSG0000004394524
Adam29 / ADAM metallopeptidase domain 29 / Q9UKF5*ENSMUSG0000004625824


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR001762  Disintegrin domain
 IPR002870  Peptidase M12B, propeptide
 IPR006586  ADAM, cysteine-rich
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR034027  Reprolysin domain, adamalysin-type
 IPR036436  Disintegrin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0030154 cell differentiation IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0005178 integrin binding ISS
 molecular_functionGO:0008237 metallopeptidase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003858 enhanced coordination "improved ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hspg2tm1Soni/Hspg2tm1Soni
Genetic Background: involves: 129S/SvEv * DBA/2J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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