ENSG00000171121


Homo sapiens

Features
Gene ID: ENSG00000171121
  
Biological name :KCNMB3
  
Synonyms : KCNMB3 / potassium calcium-activated channel subfamily M regulatory beta subunit 3 / Q9NPA1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q26.32
Gene start: 179236691
Gene end: 179267002
  
Corresponding Affymetrix probe sets: 221125_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000418536
Ensembl peptide - ENSP00000417091
Ensembl peptide - ENSP00000479162
Ensembl peptide - ENSP00000319370
Ensembl peptide - ENSP00000327866
Ensembl peptide - ENSP00000376451
Ensembl peptide - ENSP00000376452
NCBI entrez gene - 27094     See in Manteia.
OMIM - 605222
RefSeq - NM_001163677
RefSeq - NM_014407
RefSeq - NM_171828
RefSeq - NM_171829
RefSeq - NM_171830
RefSeq Peptide - NP_741980
RefSeq Peptide - NP_741981
RefSeq Peptide - NP_055222
RefSeq Peptide - NP_001157149
RefSeq Peptide - NP_741979
swissprot - A0A087WV41
swissprot - Q9NPA1
Ensembl - ENSG00000171121
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-38m6.7ENSDARG00000063129Danio rerio
 Kcnmb3ENSMUSG00000091091Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AC117457.1ENSG0000027516333
KCNMB2 / Q9Y691 / potassium calcium-activated channel subfamily M regulatory beta subunit 2ENSG0000019758433
KCNMB1 / Q16558 / potassium calcium-activated channel subfamily M regulatory beta subunit 1ENSG0000014593622
KCNMB4 / Q86W47 / potassium calcium-activated channel subfamily M regulatory beta subunit 4ENSG0000013564322


Protein motifs (from Interpro)
Interpro ID Name
 IPR003930  Potassium channel, calcium-activated, BK, beta subunit
 IPR008162  Inorganic pyrophosphatase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001508 action potential IDA
 biological_processGO:0005513 detection of calcium ion IDA
 biological_processGO:0006796 phosphate-containing compound metabolic process IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IDA
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0019228 neuronal action potential IDA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004427 inorganic diphosphatase activity IEA
 molecular_functionGO:0015269 calcium-activated potassium channel activity IDA
 molecular_functionGO:0015459 potassium channel regulator activity IBA


Pathways (from Reactome)
Pathway description
Ca2+ activated K+ channels
cGMP effects


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000138669 PRKG2 / Q13237 / protein kinase, cGMP-dependent, type II  / reaction
 ENSG00000135643 KCNMB4 / Q86W47 / potassium calcium-activated channel subfamily M regulatory beta subunit 4  / complex
 ENSG00000156113 KCNMA1 / Q12791 / potassium calcium-activated channel subfamily M alpha 1  / complex
 ENSG00000145936 KCNMB1 / Q16558 / potassium calcium-activated channel subfamily M regulatory beta subunit 1  / complex
 ENSG00000171121 KCNMB3 / Q9NPA1 / potassium calcium-activated channel subfamily M regulatory beta subunit 3  / complex
 ENSG00000197584 KCNMB2 / Q9Y691 / potassium calcium-activated channel subfamily M regulatory beta subunit 2  / complex
 ENSG00000185532 PRKG1 / Q13976 / protein kinase, cGMP-dependent, type I  / reaction






 

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