ENSG00000171446


Homo sapiens

Features
Gene ID: ENSG00000171446
  
Biological name :KRT27
  
Synonyms : keratin 27 / KRT27 / Q7Z3Y8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q21.2
Gene start: 40776808
Gene end: 40782534
  
Corresponding Affymetrix probe sets: 240388_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000301656
NCBI entrez gene - 342574     See in Manteia.
OMIM - 616676
RefSeq - NM_181537
RefSeq Peptide - NP_853515
swissprot - Q7Z3Y8
Ensembl - ENSG00000171446
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyt1ENSDARG00000092947Danio rerio
 cyt1lENSDARG00000036832Danio rerio
 krt1-19dENSDARG00000023082Danio rerio
 krt15ENSDARG00000036840Danio rerio
 krt17ENSDARG00000094041Danio rerio
 krt91ENSDARG00000036830Danio rerio
 krt92ENSDARG00000036834Danio rerio
 krt93ENSDARG00000044976Danio rerio
 krt94ENSDARG00000044975Danio rerio
 krt95ENSDARG00000014356Danio rerio
 krt96ENSDARG00000095147Danio rerio
 krt97ENSDARG00000000212Danio rerio
 krtt1c19eENSDARG00000090268Danio rerio
 si:ch211-156l18.7ENSDARG00000022334Danio rerio
 Krt27ENSMUSG00000017588Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KRT25 / Q7Z3Z0 / keratin 25ENSG0000020489780
KRT28 / Q7Z3Y7 / keratin 28ENSG0000017390878
KRT26 / Q7Z3Y9 / keratin 26ENSG0000018639373
KRT24 / Q2M2I5 / keratin 24ENSG0000016791656
KRT10 / P13645 / keratin 10ENSG0000018639556
KRT14 / P02533 / keratin 14ENSG0000018684751
KRT16 / P08779 / keratin 16ENSG0000018683251
KRT12 / Q99456 / keratin 12ENSG0000018724251
KRT13 / P13646 / keratin 13ENSG0000017140149
KRT15 / P19012 / keratin 15ENSG0000017134649
KRT17 / Q04695 / keratin 17ENSG0000012842248
KRT19 / P08727 / keratin 19ENSG0000017134543


Protein motifs (from Interpro)
Interpro ID Name
 IPR001664  Intermediate filament protein
 IPR002957  Keratin, type I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0031069 hair follicle morphogenesis IEA
 biological_processGO:0031424 keratinization TAS
 biological_processGO:0070268 cornification TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005882 intermediate filament IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005198 structural molecule activity IEA


Pathways (from Reactome)
Pathway description
Keratinization
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000171446 KRT27 / Q7Z3Y8 / keratin 27  / - / reaction / complex
 ENSG00000143631 FLG / P20930 / filaggrin  / reaction / - / complex
 ENSG00000204897 KRT25 / Q7Z3Z0 / keratin 25  / - / complex / reaction
 ENSG00000173908 KRT28 / Q7Z3Y7 / keratin 28  / reaction / complex / -
 ENSG00000186393 KRT26 / Q7Z3Y9 / keratin 26  / complex / - / reaction






 

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