ENSG00000172156


Homo sapiens

Features
Gene ID: ENSG00000172156
  
Biological name :CCL11
  
Synonyms : CCL11 / C-C motif chemokine ligand 11 / P51671
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q12
Gene start: 34285668
Gene end: 34288334
  
Corresponding Affymetrix probe sets: 210133_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000302234
NCBI entrez gene - 6356     See in Manteia.
OMIM - 601156
RefSeq - NM_002986
RefSeq Peptide - NP_002977
swissprot - P51671
swissprot - Q6I9T4
Ensembl - ENSG00000172156
  
Related genetic diseases (OMIM): 600807 - {Asthma, susceptibility to}, 600807
  609423 - {HIV1, resistance to}, 609423
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Ccl11ENSMUSG00000020676Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CCL2 / P13500 / C-C motif chemokine ligand 2ENSG0000010869171
CCL8 / P80075 / C-C motif chemokine ligand 8ENSG0000010870070
CCL7 / P80098 / C-C motif chemokine ligand 7ENSG0000010868870
CCL13 / Q99616 / C-C motif chemokine ligand 13ENSG0000018137464
CCL24 / O00175 / C-C motif chemokine ligand 24ENSG0000010617830


Protein motifs (from Interpro)
Interpro ID Name
 IPR000827  CC chemokine, conserved site
 IPR001811  Chemokine interleukin-8-like domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IDA
 biological_processGO:0002544 chronic inflammatory response IEA
 biological_processGO:0002548 monocyte chemotaxis IBA
 biological_processGO:0002551 mast cell chemotaxis IEA
 biological_processGO:0006468 protein phosphorylation TAS
 biological_processGO:0006874 cellular calcium ion homeostasis TAS
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007010 cytoskeleton organization IDA
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0007155 cell adhesion TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IBA
 biological_processGO:0008360 regulation of cell shape IDA
 biological_processGO:0009314 response to radiation TAS
 biological_processGO:0009615 response to virus TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030335 positive regulation of cell migration IDA
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0030838 positive regulation of actin filament polymerization IDA
 biological_processGO:0035962 response to interleukin-13 IEA
 biological_processGO:0043547 positive regulation of GTPase activity IDA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0048245 eosinophil chemotaxis IEA
 biological_processGO:0048247 lymphocyte chemotaxis IBA
 biological_processGO:0060444 branching involved in mammary gland duct morphogenesis IEA
 biological_processGO:0060763 mammary duct terminal end bud growth IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0070371 ERK1 and ERK2 cascade IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0070670 response to interleukin-4 IEA
 biological_processGO:0071346 cellular response to interferon-gamma IBA
 biological_processGO:0071347 cellular response to interleukin-1 IBA
 biological_processGO:0071356 cellular response to tumor necrosis factor IBA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005623 cell IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008009 chemokine activity IDA
 molecular_functionGO:0031728 CCR3 chemokine receptor binding IDA
 molecular_functionGO:0046983 protein dimerization activity IDA
 molecular_functionGO:0048018 receptor ligand activity IDA


Pathways (from Reactome)
Pathway description
Interleukin-4 and Interleukin-13 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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