ENSG00000108688


Homo sapiens

Features
Gene ID: ENSG00000108688
  
Biological name :CCL7
  
Synonyms : CCL7 / C-C motif chemokine ligand 7 / P80098
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q12
Gene start: 34270221
Gene end: 34272242
  
Corresponding Affymetrix probe sets: 208075_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000367832
Ensembl peptide - ENSP00000378126
Ensembl peptide - ENSP00000378124
NCBI entrez gene - 6354     See in Manteia.
OMIM - 158106
RefSeq - NM_006273
RefSeq Peptide - NP_006264
swissprot - A8MX17
swissprot - A8MVH1
swissprot - P80098
Ensembl - ENSG00000108688
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Ccl7ENSMUSG00000035373Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CCL2 / P13500 / C-C motif chemokine ligand 2ENSG0000010869174
CCL11 / P51671 / C-C motif chemokine ligand 11ENSG0000017215669
CCL8 / P80075 / C-C motif chemokine ligand 8ENSG0000010870065
CCL13 / Q99616 / C-C motif chemokine ligand 13ENSG0000018137462
CCL24 / O00175 / C-C motif chemokine ligand 24ENSG0000010617831


Protein motifs (from Interpro)
Interpro ID Name
 IPR000827  CC chemokine, conserved site
 IPR001811  Chemokine interleukin-8-like domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002548 monocyte chemotaxis IC
 biological_processGO:0006874 cellular calcium ion homeostasis TAS
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007010 cytoskeleton organization IDA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0008360 regulation of cell shape IDA
 biological_processGO:0010332 response to gamma radiation IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030335 positive regulation of cell migration IDA
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0048245 eosinophil chemotaxis IDA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071346 cellular response to interferon-gamma IBA
 biological_processGO:0071347 cellular response to interleukin-1 IBA
 biological_processGO:0071356 cellular response to tumor necrosis factor IBA
 biological_processGO:0071361 cellular response to ethanol IEA
 biological_processGO:2000503 positive regulation of natural killer cell chemotaxis IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0005623 cell IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008009 chemokine activity TAS
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0031726 CCR1 chemokine receptor binding IPI
 molecular_functionGO:0031727 CCR2 chemokine receptor binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr