ENSMUSG00000035373


Mus musculus

Features
Gene ID: ENSMUSG00000035373
  
Biological name :Ccl7
  
Synonyms : Ccl7 / C-C motif chemokine 7 / Q03366
  
Possible biological names infered from orthology : C-C motif chemokine ligand 7 / P80098
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: C
Gene start: 82045712
Gene end: 82047525
  
Corresponding Affymetrix probe sets: 10379518 (MoGene1.0st)   1421228_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021011
NCBI entrez gene - 20306     See in Manteia.
MGI - MGI:99512
RefSeq - NM_013654
RefSeq Peptide - NP_038682
swissprot - A9Z1Z1
swissprot - Q03366
Ensembl - ENSMUSG00000035373
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CCL7ENSG00000108688Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ccl12 / Q62401 / C-C motif chemokine 12 / CCL8* / P80075* / C-C motif chemokine ligand 8*ENSMUSG0000003535257
Ccl8 / Q9Z121 / C-C motif chemokine 8 / P80075* / C-C motif chemokine ligand 8*ENSMUSG0000000918552
Ccl2 / P10148 / C-C motif chemokine 2 / P13500* / C-C motif chemokine ligand 2*ENSMUSG0000003538549
Ccl11 / P48298 / Eotaxin / P51671* / C-C motif chemokine ligand 11*ENSMUSG0000002067646
Ccl24 / Q9JKC0 / C-C motif chemokine 24 / O00175* / C-C motif chemokine ligand 24*ENSMUSG0000000481432


Protein motifs (from Interpro)
Interpro ID Name
 IPR000827  CC chemokine, conserved site
 IPR001811  Chemokine interleukin-8-like domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002548 monocyte chemotaxis IBA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IBA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0010332 response to gamma radiation IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0048245 eosinophil chemotaxis IEA
 biological_processGO:0048247 lymphocyte chemotaxis IBA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071346 cellular response to interferon-gamma IBA
 biological_processGO:0071347 cellular response to interleukin-1 IBA
 biological_processGO:0071356 cellular response to tumor necrosis factor IBA
 biological_processGO:0071361 cellular response to ethanol IEA
 biological_processGO:2000503 positive regulation of natural killer cell chemotaxis IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0008009 chemokine activity IBA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0031726 CCR1 chemokine receptor binding IEA
 molecular_functionGO:0031727 CCR2 chemokine receptor binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002620 abnormal monocyte morphology "anomalous structure, number, or development of the white blood cells that are precursors to macrophages" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Ccl2tm1Rol/Ccl2tm1Rol
Genetic Background: involves: 129S4/SvJae

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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