ENSMUSG00000009185


Mus musculus

Features
Gene ID: ENSMUSG00000009185
  
Biological name :Ccl8
  
Synonyms : Ccl8 / C-C motif chemokine 8 / Q9Z121
  
Possible biological names infered from orthology : C-C motif chemokine ligand 8 / P80075
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: C
Gene start: 82115185
Gene end: 82116799
  
Corresponding Affymetrix probe sets: 10379535 (MoGene1.0st)   1419684_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000009329
NCBI entrez gene - 20307     See in Manteia.
MGI - MGI:101878
RefSeq - NM_021443
RefSeq Peptide - NP_067418
swissprot - Q149U7
swissprot - Q9Z121
Ensembl - ENSMUSG00000009185
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CCL8ENSG00000108700Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ccl12 / Q62401 / C-C motif chemokine 12 / CCL8* / P80075* / C-C motif chemokine ligand 8*ENSMUSG0000003535256
Ccl7 / Q03366 / C-C motif chemokine 7 / P80098* / C-C motif chemokine ligand 7*ENSMUSG0000003537352
Ccl11 / P48298 / Eotaxin / P51671* / C-C motif chemokine ligand 11*ENSMUSG0000002067641
Ccl2 / P10148 / C-C motif chemokine 2 / P13500* / C-C motif chemokine ligand 2*ENSMUSG0000003538540
Ccl24 / Q9JKC0 / C-C motif chemokine 24 / O00175* / C-C motif chemokine ligand 24*ENSMUSG0000000481430


Protein motifs (from Interpro)
Interpro ID Name
 IPR000827  CC chemokine, conserved site
 IPR001811  Chemokine interleukin-8-like domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002548 monocyte chemotaxis IBA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0045663 positive regulation of myoblast differentiation IMP
 biological_processGO:0048247 lymphocyte chemotaxis IBA
 biological_processGO:0060326 cell chemotaxis IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071346 cellular response to interferon-gamma IBA
 biological_processGO:0071347 cellular response to interleukin-1 IBA
 biological_processGO:0071356 cellular response to tumor necrosis factor IBA
 biological_processGO:1901741 positive regulation of myoblast fusion IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0008009 chemokine activity IBA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0048020 CCR chemokine receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001539 decreased number of caudal vertebrae "reduced number of the bony segments of the tail" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Catsper3tm1.1(KOMP)Vlcg/Catsper3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Catsper3tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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