ENSMUSG00000035352


Mus musculus

Features
Gene ID: ENSMUSG00000035352
  
Biological name :Ccl12
  
Synonyms : Ccl12 / C-C motif chemokine 12 / Q62401
  
Possible biological names infered from orthology : CCL8 / C-C motif chemokine ligand 8 / P80075
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: C
Gene start: 82101845
Gene end: 82103400
  
Corresponding Affymetrix probe sets: 10379530 (MoGene1.0st)   1419282_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000000194
NCBI entrez gene - 20293     See in Manteia.
MGI - MGI:108224
RefSeq - NM_011331
RefSeq Peptide - NP_035461
swissprot - Q545B5
swissprot - Q62401
Ensembl - ENSMUSG00000035352
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CCL8ENSG00000108700Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ccl7 / Q03366 / C-C motif chemokine 7 / P80098* / C-C motif chemokine ligand 7*ENSMUSG0000003537353
Ccl8 / Q9Z121 / C-C motif chemokine 8 / P80075* / C-C motif chemokine ligand 8*ENSMUSG0000000918552
Ccl11 / P48298 / Eotaxin / P51671* / C-C motif chemokine ligand 11*ENSMUSG0000002067646
Ccl2 / P10148 / C-C motif chemokine 2 / P13500* / C-C motif chemokine ligand 2*ENSMUSG0000003538545
Ccl24 / Q9JKC0 / C-C motif chemokine 24 / O00175* / C-C motif chemokine ligand 24*ENSMUSG0000000481428


Protein motifs (from Interpro)
Interpro ID Name
 IPR000827  CC chemokine, conserved site
 IPR001811  Chemokine interleukin-8-like domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade ISO
 biological_processGO:0001525 angiogenesis IDA
 biological_processGO:0002548 monocyte chemotaxis IDA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006954 inflammatory response IDA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007010 cytoskeleton organization ISO
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IBA
 biological_processGO:0008360 regulation of cell shape ISO
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway ISO
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0031663 lipopolysaccharide-mediated signaling pathway ISO
 biological_processGO:0034351 negative regulation of glial cell apoptotic process ISO
 biological_processGO:0043491 protein kinase B signaling ISO
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISO
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0043615 astrocyte cell migration ISO
 biological_processGO:0048246 macrophage chemotaxis ISO
 biological_processGO:0048247 lymphocyte chemotaxis IBA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071346 cellular response to interferon-gamma IBA
 biological_processGO:0071347 cellular response to interleukin-1 IBA
 biological_processGO:0071356 cellular response to tumor necrosis factor IBA
 biological_processGO:0071407 cellular response to organic cyclic compound ISO
 biological_processGO:0090280 positive regulation of calcium ion import ISO
 biological_processGO:2000502 negative regulation of natural killer cell chemotaxis ISO
 cellular_componentGO:0005576 extracellular region ISO
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0008009 chemokine activity IBA
 molecular_functionGO:0031727 CCR2 chemokine receptor binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr