ENSG00000172543


Homo sapiens

Features
Gene ID: ENSG00000172543
  
Biological name :CTSW
  
Synonyms : cathepsin W / CTSW / P56202
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.1
Gene start: 65879809
Gene end: 65883741
  
Corresponding Affymetrix probe sets: 214450_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000311300
Ensembl peptide - ENSP00000436568
Ensembl peptide - ENSP00000434267
NCBI entrez gene - 1521     See in Manteia.
OMIM - 602364
RefSeq - NM_001335
RefSeq Peptide - NP_001326
swissprot - E9PI30
swissprot - H0YDT2
swissprot - P56202
Ensembl - ENSG00000172543
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CtswENSMUSG00000024910Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CTSF / Q9UBX1 / cathepsin FENSG0000017408036
CTSV / O60911 / cathepsin VENSG0000013694328
CTSL / P07711 / cathepsin LENSG0000013504727
CTSS / P25774 / cathepsin SENSG0000016313126
CTSH / P09668 / cathepsin HENSG0000010381126
CTSK / P43235 / cathepsin KENSG0000014338724


Protein motifs (from Interpro)
Interpro ID Name
 IPR000668  Peptidase C1A, papain C-terminal
 IPR013128  Peptidase C1A
 IPR013201  Cathepsin propeptide inhibitor domain (I29)
 IPR025660  Cysteine peptidase, histidine active site
 IPR025661  Cysteine peptidase, asparagine active site
 IPR033158  Cathepsin W


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006955 immune response TAS
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IBA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005764 lysosome IBA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0031089 platelet dense granule lumen TAS
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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