ENSG00000173193


Homo sapiens

Features
Gene ID: ENSG00000173193
  
Biological name :PARP14
  
Synonyms : PARP14 / poly(ADP-ribose) polymerase family member 14 / Q460N5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q21.1
Gene start: 122680618
Gene end: 122730840
  
Corresponding Affymetrix probe sets: 224701_at (Human Genome U133 Plus 2.0 Array)   232610_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000418194
Ensembl peptide - ENSP00000418535
Ensembl peptide - ENSP00000420649
NCBI entrez gene - 54625     See in Manteia.
OMIM - 610028
RefSeq - XM_011512928
RefSeq - NM_017554
RefSeq Peptide - NP_060024
swissprot - H7C4Y3
swissprot - Q460N5
swissprot - H7C5R8
Ensembl - ENSG00000173193
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-219a4.3ENSDARG00000040445Danio rerio
 ENSGALG00000026422Gallus gallus
 ENSGALG00000012072Gallus gallus
 Parp14ENSMUSG00000034422Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PARP15 / Q460N3 / poly(ADP-ribose) polymerase family member 15ENSG0000017320020
PARP9 / Q8IXQ6 / poly(ADP-ribose) polymerase family member 9ENSG0000013849613
PARP10 / Q53GL7 / poly(ADP-ribose) polymerase family member 10ENSG0000017868510
Q7Z2W4 / ZC3HAV1 / zinc finger CCCH-type containing, antiviral 1ENSG000001059398
PARP12 / Q9H0J9 / poly(ADP-ribose) polymerase family member 12ENSG000000593788
Q7Z3E1 / TIPARP / TCDD inducible poly(ADP-ribose) polymeraseENSG000001636597
PARP11 / Q9NR21 / poly(ADP-ribose) polymerase family member 11ENSG000001112245


Protein motifs (from Interpro)
Interpro ID Name
 IPR002589  Macro domain
 IPR004170  WWE domain
 IPR012317  Poly(ADP-ribose) polymerase, catalytic domain
 IPR034517  PARP-14, RNA recognition motif 2
 IPR036612  K Homology domain, type 1 superfamily
 IPR037197  WWE domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006471 protein ADP-ribosylation IDA
 biological_processGO:0010629 negative regulation of gene expression IMP
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IMP
 biological_processGO:0042532 negative regulation of tyrosine phosphorylation of STAT protein IMP
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0060336 negative regulation of interferon-gamma-mediated signaling pathway IEA
 biological_processGO:1902216 positive regulation of interleukin-4-mediated signaling pathway IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane HDA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003950 NAD+ ADP-ribosyltransferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0019899 enzyme binding IPI


Pathways (from Reactome)
Pathway description
Nicotinamide salvaging


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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