ENSG00000105939


Homo sapiens

Features
Gene ID: ENSG00000105939
  
Biological name :ZC3HAV1
  
Synonyms : Q7Z2W4 / ZC3HAV1 / zinc finger CCCH-type containing, antiviral 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q34
Gene start: 139043520
Gene end: 139109719
  
Corresponding Affymetrix probe sets: 213051_at (Human Genome U133 Plus 2.0 Array)   220104_at (Human Genome U133 Plus 2.0 Array)   225634_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000420107
Ensembl peptide - ENSP00000242351
Ensembl peptide - ENSP00000418385
Ensembl peptide - ENSP00000419855
NCBI entrez gene - 56829     See in Manteia.
OMIM - 607312
RefSeq - XM_011516412
RefSeq - NM_020119
RefSeq - NM_024625
RefSeq - XM_005250501
RefSeq Peptide - NP_064504
RefSeq Peptide - NP_078901
swissprot - H7C5K1
swissprot - Q7Z2W4
swissprot - C9J6P4
Ensembl - ENSG00000105939
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 parp12bENSDARG00000057974Danio rerio
 Q3UPF5ENSMUSG00000029826Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PARP12 / Q9H0J9 / poly(ADP-ribose) polymerase family member 12ENSG0000005937826
PARP14 / Q460N5 / poly(ADP-ribose) polymerase family member 14ENSG0000017319316
Q7Z3E1 / TIPARP / TCDD inducible poly(ADP-ribose) polymeraseENSG0000016365915
PARP10 / Q53GL7 / poly(ADP-ribose) polymerase family member 10ENSG0000017868511
PARP15 / Q460N3 / poly(ADP-ribose) polymerase family member 15ENSG0000017320011
PARP9 / Q8IXQ6 / poly(ADP-ribose) polymerase family member 9ENSG0000013849611
PARP11 / Q9NR21 / poly(ADP-ribose) polymerase family member 11ENSG0000011122410


Protein motifs (from Interpro)
Interpro ID Name
 IPR000571  Zinc finger, CCCH-type
 IPR004170  WWE domain
 IPR012317  Poly(ADP-ribose) polymerase, catalytic domain
 IPR036855  Zinc finger, CCCH-type superfamily
 IPR037197  WWE domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0009615 response to virus IDA
 biological_processGO:0045071 negative regulation of viral genome replication IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0061014 positive regulation of mRNA catabolic process IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003950 NAD+ ADP-ribosyltransferase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Signaling by BRAF and RAF fusions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000105939 Q7Z2W4 / ZC3HAV1 / zinc finger CCCH-type containing, antiviral 1  / complex






 

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