ENSMUSG00000029826


Mus musculus

Features
Gene ID: ENSMUSG00000029826
  
Biological name :Zc3hav1
  
Synonyms : Q3UPF5 / Zc3hav1 / zinc finger CCCH type, antiviral 1
  
Possible biological names infered from orthology : Q7Z2W4 / zinc finger CCCH-type containing, antiviral 1
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: B1
Gene start: 38305286
Gene end: 38354603
  
Corresponding Affymetrix probe sets: 10544089 (MoGene1.0st)   1428378_at (Mouse Genome 430 2.0 Array)   1431909_at (Mouse Genome 430 2.0 Array)   1436183_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031850
Ensembl peptide - ENSMUSP00000110548
Ensembl peptide - ENSMUSP00000110550
Ensembl peptide - ENSMUSP00000144312
NCBI entrez gene - 78781     See in Manteia.
MGI - MGI:1926031
RefSeq - XM_006506781
RefSeq - NM_001347122
RefSeq - NM_028421
RefSeq - NM_028864
RefSeq - XM_006506779
RefSeq - XM_006506780
RefSeq Peptide - NP_082697
RefSeq Peptide - NP_083140
RefSeq Peptide - NP_001334051
swissprot - G3X9X5
swissprot - Q3UPF5
swissprot - D3Z5I1
Ensembl - ENSMUSG00000029826
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 parp12bENSDARG00000057974Danio rerio
 Q7Z2W4ENSG00000105939Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Parp12 / Q8BZ20 / Poly [ADP-ribose] polymerase 12 / Q9H0J9* / poly(ADP-ribose) polymerase family member 12*ENSMUSG0000003850722
Parp14 / Q2EMV9 / Poly [ADP-ribose] polymerase 14 / Q460N5* / poly(ADP-ribose) polymerase family member 14*ENSMUSG0000003442214
Q8C1B2 / Tiparp / TCDD-inducible poly(ADP-ribose) polymerase / Q7Z3E1*ENSMUSG0000003464013
Parp11 / Q8CFF0 / Mus musculus poly (ADP-ribose) polymerase family, member 11 (Parp11), transcript variant 3, mRNA. / Q9NR21* / poly(ADP-ribose) polymerase family member 11*ENSMUSG000000379979
Parp10 / poly (ADP-ribose) polymerase family, member 10 / Q53GL7*ENSMUSG000000632688
Parp9 / Q8CAS9 / Poly [ADP-ribose] polymerase 9 / Q8IXQ6* / poly(ADP-ribose) polymerase family member 9*ENSMUSG000000229068


Protein motifs (from Interpro)
Interpro ID Name
 IPR000571  Zinc finger, CCCH-type
 IPR004170  WWE domain
 IPR012317  Poly(ADP-ribose) polymerase, catalytic domain
 IPR036855  Zinc finger, CCCH-type superfamily
 IPR037197  WWE domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0009615 response to virus ISS
 biological_processGO:0032481 positive regulation of type I interferon production IDA
 biological_processGO:0032727 positive regulation of interferon-alpha production ISO
 biological_processGO:0032728 positive regulation of interferon-beta production ISO
 biological_processGO:0032781 positive regulation of ATPase activity ISO
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling ISO
 biological_processGO:0045071 negative regulation of viral genome replication ISS
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0061014 positive regulation of mRNA catabolic process ISO
 biological_processGO:0071360 cellular response to exogenous dsRNA IDA
 biological_processGO:1900246 positive regulation of RIG-I signaling pathway ISO
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IMP
 cellular_componentGO:0005770 late endosome IMP
 cellular_componentGO:0005829 cytosol ISO
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003950 NAD+ ADP-ribosyltransferase activity IEA
 molecular_functionGO:0017151 DEAD/H-box RNA helicase binding ISO
 molecular_functionGO:0045296 cadherin binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
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Allelic Composition: Scn8a9J/Scn8a9J
Genetic Background: B6J.C-Scn8a9J/Mm

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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