ENSMUSG00000037997


Mus musculus

Features
Gene ID: ENSMUSG00000037997
  
Biological name :Parp11
  
Synonyms : Mus musculus poly (ADP-ribose) polymerase family, member 11 (Parp11), transcript variant 3, mRNA. / Parp11 / Q8CFF0
  
Possible biological names infered from orthology : poly(ADP-ribose) polymerase family member 11 / Q9NR21
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: F3
Gene start: 127446840
Gene end: 127494261
  
Corresponding Affymetrix probe sets: 10542040 (MoGene1.0st)   1434139_at (Mouse Genome 430 2.0 Array)   1444029_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000107810
Ensembl peptide - ENSMUSP00000107814
Ensembl peptide - ENSMUSP00000144598
Ensembl peptide - ENSMUSP00000036127
Ensembl peptide - ENSMUSP00000107812
NCBI entrez gene - 101187     See in Manteia.
MGI - MGI:2141505
RefSeq - XM_017321286
RefSeq - NM_001346513
RefSeq - NM_181402
RefSeq - XM_006505234
RefSeq - XM_006505235
RefSeq - XM_006505236
RefSeq - XM_006505237
RefSeq - XM_017321285
RefSeq - XM_006505231
RefSeq - XM_006505232
RefSeq - XM_006505233
RefSeq Peptide - NP_001333441
RefSeq Peptide - NP_001333442
RefSeq Peptide - NP_852067
swissprot - Q8CFF0
swissprot - A0A0J9YVC5
Ensembl - ENSMUSG00000037997
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 parp11ENSDARG00000098716Danio rerio
 ENSGALG00000040332Gallus gallus
 ENSGALG00000014347Gallus gallus
 PARP11ENSG00000111224Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Parp12 / Q8BZ20 / Poly [ADP-ribose] polymerase 12 / Q9H0J9* / poly(ADP-ribose) polymerase family member 12*ENSMUSG0000003850735
Q8C1B2 / Tiparp / TCDD-inducible poly(ADP-ribose) polymerase / Q7Z3E1*ENSMUSG0000003464029
Q3UPF5 / Zc3hav1 / zinc finger CCCH type, antiviral 1 / Q7Z2W4* / zinc finger CCCH-type containing, antiviral 1*ENSMUSG0000002982628
Parp14 / Q2EMV9 / Poly [ADP-ribose] polymerase 14 / Q460N5* / poly(ADP-ribose) polymerase family member 14*ENSMUSG0000003442227
Parp10 / poly (ADP-ribose) polymerase family, member 10 / Q53GL7*ENSMUSG0000006326820
Parp9 / Q8CAS9 / Poly [ADP-ribose] polymerase 9 / Q8IXQ6* / poly(ADP-ribose) polymerase family member 9*ENSMUSG0000002290615


Protein motifs (from Interpro)
Interpro ID Name
 IPR004170  WWE domain
 IPR012317  Poly(ADP-ribose) polymerase, catalytic domain
 IPR037197  WWE domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006998 nuclear envelope organization IMP
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0051028 mRNA transport IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005643 nuclear pore IEA
 molecular_functionGO:0003950 NAD+ ADP-ribosyltransferase activity ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Cnga3cpfl5/Cnga3cpfl5
Genetic Background: B6.RHJ-Cnga3cpfl5/BocJ

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Cnga3cpfl5/Cnga3cpfl5
Genetic Background: B6.RHJ-Cnga3cpfl5/BocJ

 MP:0001932 abnormal spermiogenesis "failure of sperm cells to form or differentiate" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cnga3cpfl5/Cnga3cpfl5
Genetic Background: B6.RHJ-Cnga3cpfl5/BocJ

 MP:0005578 teratozoospermia "presence of malformed spermatozoa in the semen; malformations include the physical bending of the sperm to produce kinks or bends" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cnga3cpfl5/Cnga3cpfl5
Genetic Background: B6.RHJ-Cnga3cpfl5/BocJ

 MP:0006380 abnormal spermatid morphology "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cnga3cpfl5/Cnga3cpfl5
Genetic Background: B6.RHJ-Cnga3cpfl5/BocJ

 MP:0009230 abnormal sperm head morphology "any structural abnormality of the head segment of the sperm cell which contains the nucleus with densely coiled chromatin fibers, and is surrounded anteriorly by the acrosome which contains enzymes used for penetrating the female egg" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cnga3cpfl5/Cnga3cpfl5
Genetic Background: B6.RHJ-Cnga3cpfl5/BocJ

 MP:0009232 abnormal sperm nucleus morphology "any structural abnormality of the sperm head nucleus, including an abnormal nuclear shape or defects in the compaction of nuclear chromatin" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cnga3cpfl5/Cnga3cpfl5
Genetic Background: B6.RHJ-Cnga3cpfl5/BocJ

 MP:0009647 decreased fertilization frequency "he number of secondary oocytes each penetrated by a spermatozoon followed by fusion of the male and female pronuclei are fewer than expected" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cnga3cpfl5/Cnga3cpfl5
Genetic Background: B6.RHJ-Cnga3cpfl5/BocJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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