ENSMUSG00000022906


Mus musculus

Features
Gene ID: ENSMUSG00000022906
  
Biological name :Parp9
  
Synonyms : Parp9 / Poly [ADP-ribose] polymerase 9 / Q8CAS9
  
Possible biological names infered from orthology : poly(ADP-ribose) polymerase family member 9 / Q8IXQ6
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: B3
Gene start: 35938470
Gene end: 35972605
  
Corresponding Affymetrix probe sets: 10435457 (MoGene1.0st)   1416897_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000110527
Ensembl peptide - ENSMUSP00000123736
Ensembl peptide - ENSMUSP00000124098
Ensembl peptide - ENSMUSP00000023622
Ensembl peptide - ENSMUSP00000110528
NCBI entrez gene - 80285     See in Manteia.
MGI - MGI:1933117
RefSeq - XM_011246046
RefSeq - NM_030253
RefSeq - XM_006522755
RefSeq - XM_006522756
RefSeq - XM_006522757
RefSeq Peptide - NP_084529
swissprot - Q8CAS9
swissprot - H7BWY5
swissprot - F6U1Y8
swissprot - E0CYZ7
Ensembl - ENSMUSG00000022906
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-219a4.6ENSDARG00000006848Danio rerio
 PARP9ENSGALG00000045511Gallus gallus
 PARP9ENSG00000138496Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Parp14 / Q2EMV9 / Poly [ADP-ribose] polymerase 14 / Q460N5* / poly(ADP-ribose) polymerase family member 14*ENSMUSG0000003442225
Parp10 / poly (ADP-ribose) polymerase family, member 10 / Q53GL7*ENSMUSG0000006326814
Parp12 / Q8BZ20 / Poly [ADP-ribose] polymerase 12 / Q9H0J9* / poly(ADP-ribose) polymerase family member 12*ENSMUSG0000003850711
Q3UPF5 / Zc3hav1 / zinc finger CCCH type, antiviral 1 / Q7Z2W4* / zinc finger CCCH-type containing, antiviral 1*ENSMUSG0000002982610
Q8C1B2 / Tiparp / TCDD-inducible poly(ADP-ribose) polymerase / Q7Z3E1*ENSMUSG0000003464010
Parp11 / Q8CFF0 / Mus musculus poly (ADP-ribose) polymerase family, member 11 (Parp11), transcript variant 3, mRNA. / Q9NR21* / poly(ADP-ribose) polymerase family member 11*ENSMUSG000000379976


Protein motifs (from Interpro)
Interpro ID Name
 IPR002589  Macro domain
 IPR012317  Poly(ADP-ribose) polymerase, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0002230 positive regulation of defense response to virus by host ISO
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006302 double-strand break repair ISS
 biological_processGO:0006471 protein ADP-ribosylation ISO
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0010608 posttranscriptional regulation of gene expression ISO
 biological_processGO:0010629 negative regulation of gene expression ISO
 biological_processGO:0035563 positive regulation of chromatin binding ISO
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein ISO
 biological_processGO:0043086 negative regulation of catalytic activity ISO
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0060330 regulation of response to interferon-gamma ISO
 biological_processGO:0060335 positive regulation of interferon-gamma-mediated signaling pathway IMP
 biological_processGO:1900182 positive regulation of protein localization to nucleus ISO
 biological_processGO:2001034 positive regulation of double-strand break repair via nonhomologous end joining ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0090734 site of DNA damage ISO
 molecular_functionGO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding ISO
 molecular_functionGO:0003950 NAD+ ADP-ribosyltransferase activity ISS
 molecular_functionGO:0004857 enzyme inhibitor activity ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0042393 histone binding ISO
 molecular_functionGO:0044389 ubiquitin-like protein ligase binding ISO
 molecular_functionGO:0072570 ADP-D-ribose binding ISO
 molecular_functionGO:0097677 STAT family protein binding ISO


Pathways (from Reactome)
Pathway description
Nicotinamide salvaging


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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