ENSG00000173208


Homo sapiens

Features
Gene ID: ENSG00000173208
  
Biological name :ABCD2
  
Synonyms : ABCD2 / ATP binding cassette subfamily D member 2 / Q9UBJ2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q12
Gene start: 39550033
Gene end: 39619751
  
Corresponding Affymetrix probe sets: 207583_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000310688
NCBI entrez gene - 225     See in Manteia.
OMIM - 601081
RefSeq - XM_017018992
RefSeq - NM_005164
RefSeq - XM_011538027
RefSeq Peptide - NP_005155
swissprot - Q9UBJ2
Ensembl - ENSG00000173208
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 abcd2ENSDARG00000059409Danio rerio
 ABCD2ENSGALG00000042554Gallus gallus
 Abcd2ENSMUSG00000055782Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ABCD1 / P33897 / ATP binding cassette subfamily D member 1ENSG0000010198664
ABCD3 / P28288 / ATP binding cassette subfamily D member 3ENSG0000011752836
ABCD4 / O14678 / ATP binding cassette subfamily D member 4ENSG0000011968822


Protein motifs (from Interpro)
Interpro ID Name
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR011527  ABC transporter type 1, transmembrane domain
 IPR017871  ABC transporter, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031239  ATP-binding cassette sub-family D member 2
 IPR036640  ABC transporter type 1, transmembrane domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000038 very long-chain fatty acid metabolic process IDA
 biological_processGO:0006635 fatty acid beta-oxidation IGI
 biological_processGO:0015909 long-chain fatty acid transport IEA
 biological_processGO:0032000 positive regulation of fatty acid beta-oxidation IDA
 biological_processGO:0042760 very long-chain fatty acid catabolic process IGI
 biological_processGO:0055085 transmembrane transport TAS
 cellular_componentGO:0005777 peroxisome IDA
 cellular_componentGO:0005778 peroxisomal membrane TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005324 long-chain fatty acid transporter activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA


Pathways (from Reactome)
Pathway description
ABC transporters in lipid homeostasis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000101986 ABCD1 / P33897 / ATP binding cassette subfamily D member 1  / complex
 ENSG00000162735 PEX19 / P40855 / peroxisomal biogenesis factor 19  / complex
 ENSG00000117528 ABCD3 / P28288 / ATP binding cassette subfamily D member 3  / complex
 ENSG00000034693 PEX3 / P56589 / peroxisomal biogenesis factor 3  / reaction






 

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