ENSG00000173253


Homo sapiens

Features
Gene ID: ENSG00000173253
  
Biological name :DMRT2
  
Synonyms : DMRT2 / doublesex and mab-3 related transcription factor 2 / Q9Y5R5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: p24.3
Gene start: 1049858
Gene end: 1057552
  
Corresponding Affymetrix probe sets: 223704_s_at (Human Genome U133 Plus 2.0 Array)   223986_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000397494
Ensembl peptide - ENSP00000371690
Ensembl peptide - ENSP00000489226
Ensembl peptide - ENSP00000259622
Ensembl peptide - ENSP00000305785
Ensembl peptide - ENSP00000350865
Ensembl peptide - ENSP00000371686
NCBI entrez gene - 10655     See in Manteia.
OMIM - 604935
RefSeq - XM_017014216
RefSeq - NM_001130865
RefSeq - NM_006557
RefSeq - NM_181872
RefSeq - XM_011517687
RefSeq - XM_011517690
RefSeq - XM_017014213
RefSeq - XM_017014214
RefSeq - XM_017014215
RefSeq Peptide - NP_001124337
RefSeq Peptide - NP_006548
RefSeq Peptide - NP_870987
swissprot - A0A0A0MR18
swissprot - Q05C20
swissprot - Q9Y5R5
Ensembl - ENSG00000173253
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dmrt2aENSDARG00000015072Danio rerio
 DMRT2ENSGALG00000026790Gallus gallus
 Dmrt2ENSMUSG00000048138Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DMRTA2 / Q96SC8 / DMRT like family A2ENSG0000014270021
DMRT3 / Q9NQL9 / doublesex and mab-3 related transcription factor 3ENSG0000006421820
DMRTA1 / Q5VZB9 / DMRT like family A1ENSG0000017639918
DMRT1 / Q9Y5R6 / doublesex and mab-3 related transcription factor 1ENSG0000013709016
DMRTC2 / Q8IXT2 / DMRT like family C2ENSG0000014202513
DMRTB1 / Q96MA1 / DMRT like family B with proline rich C-terminal 1ENSG0000014300612
DMRTC1 / Q5HYR2 / DMRT like family C1ENSG000002695025
Q5HYR2 / DMRTC1B / DMRT like family C1BENSG000001849115


Protein motifs (from Interpro)
Interpro ID Name
 IPR001275  DM DNA-binding domain
 IPR026607  DMRT/protein doublesex/protein male abnormal 3
 IPR036407  DM DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0014807 regulation of somitogenesis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048706 embryonic skeletal system development IEA
 biological_processGO:2000287 positive regulation of myotome development IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr