ENSG00000142700


Homo sapiens

Features
Gene ID: ENSG00000142700
  
Biological name :DMRTA2
  
Synonyms : DMRTA2 / DMRT like family A2 / Q96SC8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p32.3
Gene start: 50417550
Gene end: 50423500
  
Corresponding Affymetrix probe sets: 1558856_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000383909
Ensembl peptide - ENSP00000399370
NCBI entrez gene - 63950     See in Manteia.
OMIM - 614804
RefSeq - XM_011541937
RefSeq - NM_032110
RefSeq Peptide - NP_115486
swissprot - Q96SC8
Ensembl - ENSG00000142700
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dmrta2ENSDARG00000039412Danio rerio
 DMRTA2ENSGALG00000031423Gallus gallus
 A2A9A2ENSMUSG00000047143Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DMRTA1 / Q5VZB9 / DMRT like family A1ENSG0000017639933
DMRT3 / Q9NQL9 / doublesex and mab-3 related transcription factor 3ENSG0000006421827
DMRT2 / Q9Y5R5 / doublesex and mab-3 related transcription factor 2ENSG0000017325321
DMRTB1 / Q96MA1 / DMRT like family B with proline rich C-terminal 1ENSG0000014300617
DMRT1 / Q9Y5R6 / doublesex and mab-3 related transcription factor 1ENSG0000013709017
DMRTC2 / Q8IXT2 / DMRT like family C2ENSG0000014202515
DMRTC1 / Q5HYR2 / DMRT like family C1ENSG000002695026
Q5HYR2 / DMRTC1B / DMRT like family C1BENSG000001849116


Protein motifs (from Interpro)
Interpro ID Name
 IPR001275  DM DNA-binding domain
 IPR005173  DMRTA motif
 IPR009060  UBA-like superfamily
 IPR026607  DMRT/protein doublesex/protein male abnormal 3
 IPR036407  DM DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002052 positive regulation of neuroblast proliferation IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007420 brain development IBA
 biological_processGO:0021796 cerebral cortex regionalization IEA
 biological_processGO:0035914 skeletal muscle cell differentiation IEA
 biological_processGO:0048665 neuron fate specification IEA
 biological_processGO:0071542 dopaminergic neuron differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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