ENSG00000142025


Homo sapiens

Features
Gene ID: ENSG00000142025
  
Biological name :DMRTC2
  
Synonyms : DMRTC2 / DMRT like family C2 / Q8IXT2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.2
Gene start: 41844743
Gene end: 41852333
  
Corresponding Affymetrix probe sets: 236811_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000472215
Ensembl peptide - ENSP00000472159
Ensembl peptide - ENSP00000472488
Ensembl peptide - ENSP00000269945
Ensembl peptide - ENSP00000469525
Ensembl peptide - ENSP00000470553
NCBI entrez gene - 63946     See in Manteia.
OMIM - 614806
RefSeq - XM_017027129
RefSeq - XM_017027123
RefSeq - XM_017027124
RefSeq - XM_017027125
RefSeq - XM_017027126
RefSeq - XM_017027127
RefSeq - XM_017027128
RefSeq - NM_001040283
RefSeq - XM_011527214
RefSeq - XM_011527215
RefSeq - XM_011527216
RefSeq Peptide - NP_001035373
swissprot - M0QZH7
swissprot - M0R1Z9
swissprot - M0R2D7
swissprot - B4DX56
swissprot - Q8IXT2
Ensembl - ENSG00000142025
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dmrt2bENSDARG00000070013Danio rerio
 Dmrtc2ENSMUSG00000011349Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5HYR2 / DMRTC1B / DMRT like family C1BENSG0000018491126
DMRTC1 / Q5HYR2 / DMRT like family C1ENSG0000026950226
DMRTA2 / Q96SC8 / DMRT like family A2ENSG0000014270023
DMRT3 / Q9NQL9 / doublesex and mab-3 related transcription factor 3ENSG0000006421821
DMRT2 / Q9Y5R5 / doublesex and mab-3 related transcription factor 2ENSG0000017325320
DMRTA1 / Q5VZB9 / DMRT like family A1ENSG0000017639920
DMRT1 / Q9Y5R6 / doublesex and mab-3 related transcription factor 1ENSG0000013709017
DMRTB1 / Q96MA1 / DMRT like family B with proline rich C-terminal 1ENSG0000014300616


Protein motifs (from Interpro)
Interpro ID Name
 IPR001275  DM DNA-binding domain
 IPR026607  DMRT/protein doublesex/protein male abnormal 3
 IPR031577  Doublesex- and mab-3-related transcription factor C1/C2, C-terminal
 IPR036407  DM DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007141 male meiosis I IEA
 biological_processGO:0007290 spermatid nucleus elongation IEA
 biological_processGO:0007548 sex differentiation IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:1900111 positive regulation of histone H3-K9 dimethylation IEA
 biological_processGO:1900114 positive regulation of histone H3-K9 trimethylation IEA
 cellular_componentGO:0001741 XY body IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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