ENSG00000176009


Homo sapiens

Features
Gene ID: ENSG00000176009
  
Biological name :ASCL3
  
Synonyms : achaete-scute family bHLH transcription factor 3 / ASCL3 / Q9NQ33
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p15.4
Gene start: 8937579
Gene end: 8938211
  
Corresponding Affymetrix probe sets: 221161_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000435770
NCBI entrez gene - 56676     See in Manteia.
OMIM - 609154
RefSeq - NM_020646
RefSeq Peptide - NP_065697
swissprot - Q9NQ33
Ensembl - ENSG00000176009
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ASCL3ENSGALG00000036725Gallus gallus
 Ascl3ENSMUSG00000035951Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASCL5 / Q7RTU5 / achaete-scute family bHLH transcription factor 5ENSG0000023223738
ASCL4 / Q6XD76 / achaete-scute family bHLH transcription factor 4ENSG0000018785533
ASCL1 / P50553 / achaete-scute family bHLH transcription factor 1ENSG0000013935225
ASCL2 / Q99929 / achaete-scute family bHLH transcription factor 2ENSG0000018373423


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR015660  Achaete-scute transcription factor-related
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IBA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding ISS
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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