ENSMUSG00000035951


Mus musculus

Features
Gene ID: ENSMUSG00000035951
  
Biological name :Ascl3
  
Synonyms : Achaete-scute homolog 3 / Ascl3 / Q9JJR7
  
Possible biological names infered from orthology : achaete-scute family bHLH transcription factor 3 / Q9NQ33
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: E3
Gene start: 109727465
Gene end: 109731726
  
Corresponding Affymetrix probe sets: 10566800 (MoGene1.0st)   1420780_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000037702
NCBI entrez gene - 56787     See in Manteia.
MGI - MGI:1928820
RefSeq - NM_020051
RefSeq Peptide - NP_064435
swissprot - Q9JJR7
Ensembl - ENSMUSG00000035951
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ASCL3ENSGALG00000036725Gallus gallus
 ASCL3ENSG00000176009Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ascl5 / achaete-scute family bHLH transcription factor 5 / Q7RTU5*ENSMUSG0000009791839
Ascl4 / achaete-scute family bHLH transcription factor 4 / Q6XD76*ENSMUSG0000008511131
Ascl1 / Q02067 / Achaete-scute homolog 1 / P50553* / achaete-scute family bHLH transcription factor 1*ENSMUSG0000002005226
Ascl2 / O35885 / Achaete-scute homolog 2 / Q99929* / achaete-scute family bHLH transcription factor 2*ENSMUSG0000000924826


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR015660  Achaete-scute transcription factor-related
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005667 transcription factor complex IPI
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IBA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Zfp568Gt(RRU161)Byg/Zfp568chato
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Ascl3tm1.1(EGFP/cre)Ovi/Ascl3+
Genetic Background: B6.129S1(Cg)-Ascl3tm1.1(EGFP/cre)Ovi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr