ENSG00000187855


Homo sapiens

Features
Gene ID: ENSG00000187855
  
Biological name :ASCL4
  
Synonyms : achaete-scute family bHLH transcription factor 4 / ASCL4 / Q6XD76
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q23.3
Gene start: 107774385
Gene end: 107776644
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000345420
NCBI entrez gene - 121549     See in Manteia.
OMIM - 609155
RefSeq - NM_203436
RefSeq Peptide - NP_982260
swissprot - Q6XD76
Ensembl - ENSG00000187855
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ASCL4ENSGALG00000019304Gallus gallus
 Ascl4ENSMUSG00000085111Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASCL5 / Q7RTU5 / achaete-scute family bHLH transcription factor 5ENSG0000023223737
ASCL3 / Q9NQ33 / achaete-scute family bHLH transcription factor 3ENSG0000017600934
ASCL1 / P50553 / achaete-scute family bHLH transcription factor 1ENSG0000013935228
ASCL2 / Q99929 / achaete-scute family bHLH transcription factor 2ENSG0000018373428


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR015660  Achaete-scute transcription factor-related
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0043588 skin development NAS
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IBA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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