ENSG00000176601


Homo sapiens

Features
Gene ID: ENSG00000176601
  
Biological name :MAP3K19
  
Synonyms : MAP3K19 / mitogen-activated protein kinase kinase kinase 19 / Q56UN5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q21.3
Gene start: 134964491
Gene end: 135047468
  
Corresponding Affymetrix probe sets: 1555804_a_at (Human Genome U133 Plus 2.0 Array)   221180_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000376650
Ensembl peptide - ENSP00000392827
Ensembl peptide - ENSP00000489676
Ensembl peptide - ENSP00000416345
Ensembl peptide - ENSP00000351140
Ensembl peptide - ENSP00000365004
Ensembl peptide - ENSP00000365005
Ensembl peptide - ENSP00000376647
Ensembl peptide - ENSP00000376649
NCBI entrez gene - 80122     See in Manteia.
RefSeq - XM_017005007
RefSeq - NM_001321177
RefSeq - NM_025052
RefSeq - XM_011511891
RefSeq - XM_011511892
RefSeq - XM_011511894
RefSeq - XM_011511896
RefSeq - XM_011511897
RefSeq - XM_017005003
RefSeq - XM_017005004
RefSeq - XM_017005005
RefSeq - XM_017005006
RefSeq - NM_001018044
RefSeq - NM_001018046
RefSeq - NM_001018047
RefSeq - NM_001282883
RefSeq Peptide - NP_001018056
RefSeq Peptide - NP_001018057
RefSeq Peptide - NP_001269812
RefSeq Peptide - NP_001308106
RefSeq Peptide - NP_079328
RefSeq Peptide - NP_001018054
swissprot - A8MWG7
swissprot - H7C041
swissprot - C9JGQ2
swissprot - Q56UN5
swissprot - A0A1B0GTF4
Ensembl - ENSG00000176601
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 map3k19ENSDARG00000094272Danio rerio
 MAP3K19ENSGALG00000028457Gallus gallus
 E9Q3S4ENSMUSG00000051590Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAP3K1 / Q13233 / mitogen-activated protein kinase kinase kinase 1ENSG0000009501517
MAP3K3 / Q99759 / mitogen-activated protein kinase kinase kinase 3ENSG0000019890916
MAP3K2 / Q9Y2U5 / mitogen-activated protein kinase kinase kinase 2ENSG0000016996716
Q99558 / MAP3K14 / mitogen-activated protein kinase kinase kinase 14ENSG0000000606211
MAP3K8 / P41279 / mitogen-activated protein kinase kinase kinase 8ENSG000001079688


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0023014 signal transduction by protein phosphorylation IBA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0032147 activation of protein kinase activity IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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