ENSG00000179115


Homo sapiens

Features
Gene ID: ENSG00000179115
  
Biological name :FARSA
  
Synonyms : FARSA / phenylalanyl-tRNA synthetase alpha subunit / Q9Y285
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.13
Gene start: 12922479
Gene end: 12934037
  
Corresponding Affymetrix probe sets: 202159_at (Human Genome U133 Plus 2.0 Array)   216602_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000320309
Ensembl peptide - ENSP00000465402
Ensembl peptide - ENSP00000467384
Ensembl peptide - ENSP00000468051
Ensembl peptide - ENSP00000468068
Ensembl peptide - ENSP00000468384
Ensembl peptide - ENSP00000396548
NCBI entrez gene - 2193     See in Manteia.
OMIM - 602918
RefSeq - NM_004461
RefSeq Peptide - NP_004452
swissprot - Q9Y285
swissprot - K7EK06
swissprot - K7EPH2
swissprot - K7ER00
swissprot - K7ER16
swissprot - K7ERS0
swissprot - Q6IBR2
Ensembl - ENSG00000179115
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 farsaENSDARG00000098825Danio rerio
 FARSAENSGALG00000040258Gallus gallus
 FarsaENSMUSG00000003808Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002319  Phenylalanyl-tRNA synthetase
 IPR004529  Phenylalanyl-tRNA synthetase, class IIc, alpha subunit
 IPR006195  Aminoacyl-tRNA synthetase, class II
 IPR013196  Helix-turn-helix, type 11
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006418 tRNA aminoacylation for protein translation TAS
 biological_processGO:0006432 phenylalanyl-tRNA aminoacylation IEA
 biological_processGO:0043039 tRNA aminoacylation IEA
 biological_processGO:0051290 protein heterotetramerization IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0009328 phenylalanine-tRNA ligase complex IDA
 cellular_componentGO:0016020 membrane HDA
 molecular_functionGO:0000049 tRNA binding IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0004812 aminoacyl-tRNA ligase activity IEA
 molecular_functionGO:0004826 phenylalanine-tRNA ligase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
Cytosolic tRNA aminoacylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000179115 FARSA / Q9Y285 / phenylalanyl-tRNA synthetase alpha subunit  / complex
 ENSG00000116120 FARSB / Q9NSD9 / phenylalanyl-tRNA synthetase beta subunit  / complex






 

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