ENSG00000179262


Homo sapiens

Features
Gene ID: ENSG00000179262
  
Biological name :RAD23A
  
Synonyms : P54725 / RAD23A / RAD23 homolog A, nucleotide excision repair protein
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.13
Gene start: 12945855
Gene end: 12953642
  
Corresponding Affymetrix probe sets: 201039_s_at (Human Genome U133 Plus 2.0 Array)   201046_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467628
Ensembl peptide - ENSP00000467024
Ensembl peptide - ENSP00000468674
Ensembl peptide - ENSP00000466243
Ensembl peptide - ENSP00000466226
Ensembl peptide - ENSP00000321365
Ensembl peptide - ENSP00000466968
NCBI entrez gene - 5886     See in Manteia.
OMIM - 600061
RefSeq - NM_001270362
RefSeq - NM_005053
RefSeq - NM_001270363
RefSeq Peptide - NP_001257292
RefSeq Peptide - NP_001257291
RefSeq Peptide - NP_005044
swissprot - P54725
swissprot - A0A024R7G8
swissprot - K7ELU6
swissprot - K7ELW1
swissprot - K7ENJ0
swissprot - K7EQ16
Ensembl - ENSG00000179262
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rad23aaENSDARG00000020001Danio rerio
 RAD23AENSGALG00000033532Gallus gallus
 P54726ENSMUSG00000003813Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P54727 / RAD23B / RAD23 homolog B, nucleotide excision repair proteinENSG0000011931863


Protein motifs (from Interpro)
Interpro ID Name
 IPR000626  Ubiquitin domain
 IPR004806  UV excision repair protein Rad23
 IPR006636  Heat shock chaperonin-binding
 IPR009060  UBA-like superfamily
 IPR015360  XPC-binding domain
 IPR015940  Ubiquitin-associated domain
 IPR029071  Ubiquitin-like domain superfamily
 IPR036353  XPC-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006289 nucleotide-excision repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0031648 protein destabilization IMP
 biological_processGO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IMP
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0045070 positive regulation of viral genome replication IMP
 biological_processGO:0045787 positive regulation of cell cycle IMP
 cellular_componentGO:0000502 proteasome complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005815 microtubule organizing center IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0032991 protein-containing complex IMP
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0003684 damaged DNA binding IEA
 molecular_functionGO:0003697 single-stranded DNA binding TAS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019900 kinase binding IPI
 molecular_functionGO:0031593 polyubiquitin modification-dependent protein binding IDA
 molecular_functionGO:1990381 ubiquitin-specific protease binding IPI


Pathways (from Reactome)
Pathway description
Josephin domain DUBs
DNA Damage Recognition in GG-NER
Formation of Incision Complex in GG-NER


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000066427 ATXN3 / P54252 / ataxin 3  / reaction / complex






 

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