ENSG00000180530


Homo sapiens

Features
Gene ID: ENSG00000180530
  
Biological name :NRIP1
  
Synonyms : NRIP1 / nuclear receptor interacting protein 1 / P48552
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: -1
Band: q21.1
Gene start: 14961235
Gene end: 15065936
  
Corresponding Affymetrix probe sets: 202599_s_at (Human Genome U133 Plus 2.0 Array)   202600_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000490103
Ensembl peptide - ENSP00000383060
Ensembl peptide - ENSP00000383063
Ensembl peptide - ENSP00000412114
Ensembl peptide - ENSP00000327213
NCBI entrez gene - 8204     See in Manteia.
OMIM - 602490
RefSeq - XM_017028476
RefSeq - XM_011529752
RefSeq - XM_017028473
RefSeq - XM_017028474
RefSeq - XM_017028475
RefSeq - NM_003489
RefSeq - XM_005261063
RefSeq - XM_005261065
RefSeq - XM_011529747
RefSeq - XM_011529748
RefSeq - XM_011529749
RefSeq - XM_011529751
RefSeq Peptide - NP_003480
swissprot - C9J130
swissprot - A0A1B0GUG9
swissprot - P48552
Ensembl - ENSG00000180530
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nrip1aENSDARG00000068965Danio rerio
 nrip1bENSDARG00000068894Danio rerio
 NRIP1ENSGALG00000015681Gallus gallus
 Nrip1ENSMUSG00000048490Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026649  Nuclear receptor-interacting protein 1
 IPR031405  Nuclear receptor-interacting protein 1, repression domain 1
 IPR031406  Nuclear receptor-interacting protein 1, repression domain 2
 IPR031407  Nuclear receptor-interacting protein 1, repression domain 3
 IPR031408  Nuclear receptor-interacting protein 1, repression domain 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0001543 ovarian follicle rupture IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007623 circadian rhythm IEP
 biological_processGO:0019915 lipid storage IEA
 biological_processGO:0030521 androgen receptor signaling pathway NAS
 biological_processGO:0030728 ovulation IEA
 biological_processGO:0032922 circadian regulation of gene expression IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated NAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0071392 cellular response to estradiol stimulus IDA
 cellular_componentGO:0000118 histone deacetylase complex IEA
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0001046 core promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003712 transcription coregulator activity IEA
 molecular_functionGO:0003713 transcription coactivator activity NAS
 molecular_functionGO:0003714 transcription corepressor activity IDA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030331 estrogen receptor binding IPI
 molecular_functionGO:0035257 nuclear hormone receptor binding IPI
 molecular_functionGO:0035259 glucocorticoid receptor binding IPI
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0042974 retinoic acid receptor binding IEA
 molecular_functionGO:0046965 retinoid X receptor binding IEA
 molecular_functionGO:0050681 androgen receptor binding NAS


Pathways (from Reactome)
Pathway description
SUMOylation of transcription cofactors
Circadian Clock
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100393 EP300 / Q09472 / E1A binding protein p300  / complex
 ENSG00000116030 SUMO1 / P63165 / small ubiquitin-like modifier 1  / complex / reaction
 ENSG00000109819 Q9UBK2 / PPARGC1A / PPARG coactivator 1 alpha  / complex
 ENSG00000103275 UBE2I / P63279 / ubiquitin conjugating enzyme E2 I  / reaction
 ENSG00000069667 RORA / P35398 / RAR related orphan receptor A  / complex






 

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