ENSG00000182568


Homo sapiens

Features
Gene ID: ENSG00000182568
  
Biological name :SATB1
  
Synonyms : Q01826 / SATB1 / SATB homeobox 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p24.3
Gene start: 18345387
Gene end: 18445588
  
Corresponding Affymetrix probe sets: 203408_s_at (Human Genome U133 Plus 2.0 Array)   241365_at (Human Genome U133 Plus 2.0 Array)   244267_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000390529
Ensembl peptide - ENSP00000391344
Ensembl peptide - ENSP00000480000
Ensembl peptide - ENSP00000479866
Ensembl peptide - ENSP00000453908
Ensembl peptide - ENSP00000408871
Ensembl peptide - ENSP00000406727
Ensembl peptide - ENSP00000402982
Ensembl peptide - ENSP00000399708
Ensembl peptide - ENSP00000399518
Ensembl peptide - ENSP00000398072
Ensembl peptide - ENSP00000394520
Ensembl peptide - ENSP00000341024
NCBI entrez gene - 6304     See in Manteia.
OMIM - 602075
RefSeq - XM_011533990
RefSeq - NM_001131010
RefSeq - NM_001195470
RefSeq - NM_001322871
RefSeq - NM_001322872
RefSeq - NM_001322873
RefSeq - NM_001322874
RefSeq - NM_001322875
RefSeq - NM_001322876
RefSeq - NM_002971
RefSeq - XM_011533988
RefSeq - XM_011533989
RefSeq Peptide - NP_001309801
RefSeq Peptide - NP_001309802
RefSeq Peptide - NP_001309803
RefSeq Peptide - NP_001309804
RefSeq Peptide - NP_001309805
RefSeq Peptide - NP_002962
RefSeq Peptide - NP_001124482
RefSeq Peptide - NP_001182399
RefSeq Peptide - NP_001309800
swissprot - H0YN86
swissprot - C9JLL5
swissprot - C9JGL9
swissprot - C9J7F3
swissprot - C9J3I0
swissprot - C9IZC5
swissprot - A0A1D5RMP0
swissprot - A0A087WW75
swissprot - A0A087WW22
swissprot - Q01826
swissprot - C9JP21
swissprot - A0A024R2H1
Ensembl - ENSG00000182568
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 satb1bENSDARG00000062621Danio rerio
 SATB1ENSGALG00000011254Gallus gallus
 Satb1ENSMUSG00000023927Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SATB2 / Q9UPW6 / SATB homeobox 2ENSG0000011904257


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR003350  CUT domain
 IPR009057  Homeobox-like domain superfamily
 IPR010982  Lambda repressor-like, DNA-binding domain superfamily
 IPR032355  SATB, CUT1-like DNA-binding domain
 IPR032392  SATB, ubiquitin-like oligomerisation domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0006325 chromatin organization TAS
 biological_processGO:0006338 chromatin remodeling IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008544 epidermis development IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016571 histone methylation IEA
 biological_processGO:0042110 T cell activation IEA
 biological_processGO:0043367 CD4-positive, alpha-beta T cell differentiation IEA
 biological_processGO:0043374 CD8-positive, alpha-beta T cell differentiation IEA
 biological_processGO:0050798 activated T cell proliferation IEA
 biological_processGO:0060004 reflex IEA
 biological_processGO:0097194 execution phase of apoptosis TAS
 cellular_componentGO:0000785 chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005720 nuclear heterochromatin IEA
 cellular_componentGO:0016363 nuclear matrix IEA
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0016605 PML body IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding TAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Apoptotic cleavage of cellular proteins
SUMOylation of chromatin organization proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000138794 CASP6 / P55212 / caspase 6  / reaction
 ENSG00000116030 SUMO1 / P63165 / small ubiquitin-like modifier 1  / reaction / complex
 ENSG00000103275 UBE2I / P63279 / ubiquitin conjugating enzyme E2 I  / reaction
 ENSG00000188612 SUMO2 / P61956 / small ubiquitin-like modifier 2  / reaction
 ENSG00000184900 SUMO3 / P55854 / small ubiquitin-like modifier 3  / reaction






 

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