ENSG00000185697


Homo sapiens

Features
Gene ID: ENSG00000185697
  
Biological name :MYBL1
  
Synonyms : MYBL1 / MYB proto-oncogene like 1 / P10243
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q13.1
Gene start: 66562175
Gene end: 66614247
  
Corresponding Affymetrix probe sets: 213906_at (Human Genome U133 Plus 2.0 Array)   231268_at (Human Genome U133 Plus 2.0 Array)   237014_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000429633
Ensembl peptide - ENSP00000428011
Ensembl peptide - ENSP00000428265
NCBI entrez gene - 4603     See in Manteia.
OMIM - 159405
RefSeq - XM_017013459
RefSeq - NM_001080416
RefSeq - NM_001144755
RefSeq - NM_001294282
RefSeq - XM_011517535
RefSeq - XM_017013455
RefSeq - XM_017013456
RefSeq - XM_017013457
RefSeq - XM_017013458
RefSeq - XM_011517533
RefSeq Peptide - NP_001073885
RefSeq Peptide - NP_001138227
RefSeq Peptide - NP_001281211
swissprot - P10243
swissprot - E7EWZ1
Ensembl - ENSG00000185697
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mybl1ENSDARG00000030999Danio rerio
 MYBL1ENSGALG00000033304Gallus gallus
 Mybl1ENSMUSG00000025912Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MYB / P10242 / MYB proto-oncogene, transcription factorENSG0000011851345
MYBL2 / P10244 / MYB proto-oncogene like 2ENSG0000010105737
Q5SXM2 / SNAPC4 / small nuclear RNA activating complex polypeptide 4ENSG0000016568417


Protein motifs (from Interpro)
Interpro ID Name
 IPR001005  SANT/Myb domain
 IPR009057  Homeobox-like domain superfamily
 IPR012642  Transcription regulator Wos2-domain
 IPR015395  C-myb, C-terminal
 IPR017930  Myb domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007141 male meiosis I ISS
 biological_processGO:0007283 spermatogenesis ISS
 biological_processGO:0010529 negative regulation of transposition ISS
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated NAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:1990511 piRNA biosynthetic process ISS
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting IBA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
PIWI-interacting RNA (piRNA) biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr