ENSG00000187164


Homo sapiens

Features
Gene ID: ENSG00000187164
  
Biological name :SHTN1
  
Synonyms : A0MZ66 / shootin 1 / SHTN1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q25.3
Gene start: 116881482
Gene end: 117126586
  
Corresponding Affymetrix probe sets: 221802_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000260777
Ensembl peptide - ENSP00000376635
Ensembl peptide - ENSP00000376636
Ensembl peptide - ENSP00000480109
Ensembl peptide - ENSP00000347532
NCBI entrez gene - 57698     See in Manteia.
OMIM - 611171
RefSeq - XM_017016462
RefSeq - NM_001127211
RefSeq - NM_001258298
RefSeq - NM_001258299
RefSeq - NM_001258300
RefSeq - NM_018330
RefSeq - XM_005270002
RefSeq - XM_006717931
RefSeq Peptide - NP_001245228
RefSeq Peptide - NP_001245229
RefSeq Peptide - NP_060800
RefSeq Peptide - NP_001120683
RefSeq Peptide - NP_001245227
swissprot - A0MZ66
Ensembl - ENSG00000187164
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 shtn1ENSDARG00000039697Danio rerio
 SHTN1ENSGALG00000030276Gallus gallus
 Shtn1ENSMUSG00000041362Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR024849  Shootin-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006930 substrate-dependent cell migration, cell extension ISS
 biological_processGO:0007265 Ras protein signal transduction ISS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007409 axonogenesis ISS
 biological_processGO:0032488 Cdc42 protein signal transduction ISS
 biological_processGO:0038007 netrin-activated signaling pathway ISS
 biological_processGO:0045773 positive regulation of axon extension ISS
 biological_processGO:0048812 neuron projection morphogenesis IEA
 biological_processGO:0060327 cytoplasmic actin-based contraction involved in cell motility ISS
 biological_processGO:0061163 endoplasmic reticulum polarization IEA
 biological_processGO:0061573 actin filament bundle retrograde transport ISS
 biological_processGO:2000114 regulation of establishment of cell polarity IEA
 biological_processGO:2001222 regulation of neuron migration IEA
 biological_processGO:2001224 positive regulation of neuron migration IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005875 microtubule associated complex IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:0030027 lamellipodium ISS
 cellular_componentGO:0030175 filopodium ISS
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0030426 growth cone ISS
 cellular_componentGO:0031252 cell leading edge IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043204 perikaryon ISS
 cellular_componentGO:0044295 axonal growth cone IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019894 kinesin binding IEA
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0051015 actin filament binding ISS


Pathways (from Reactome)
Pathway description
Recycling pathway of L1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000184009 ACTG1 / P63261 / actin gamma 1  / complex / reaction
 ENSG00000075624 ACTB / P60709 / actin beta  / complex / reaction
 ENSG00000198910 L1CAM / P32004 / L1 cell adhesion molecule  / complex / reaction






 

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