ENSG00000187733


Homo sapiens

Features
Gene ID: ENSG00000187733
  
Biological name :AMY1C
  
Synonyms : AMY1C / amylase, alpha 1C (salivary) / P04745
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p21.1
Gene start: 103750406
Gene end: 103758690
  
Corresponding Affymetrix probe sets: 208498_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000359096
NCBI entrez gene - 278     See in Manteia.
RefSeq - XM_011541263
RefSeq - NM_001008219
RefSeq - XM_017001058
RefSeq Peptide - NP_001008220
swissprot - P04745
Ensembl - ENSG00000187733
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 amy2aENSDARG00000013856Danio rerio
 zgc:66313ENSDARG00000030357Danio rerio
 zgc:92137ENSDARG00000009443Danio rerio
 AMY1AENSGALG00000005147Gallus gallus
 AMY2AENSGALG00000038740Gallus gallus
 Amy1ENSMUSG00000074264Mus musculus
 Amy2ENSMUSG00000074268Mus musculus
 Amy2a1ENSMUSG00000070360Mus musculus
 Amy2a2ENSMUSG00000096569Mus musculus
 Amy2a3ENSMUSG00000093931Mus musculus
 Amy2a4ENSMUSG00000096770Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AMY1B / P04745 / amylase, alpha 1B (salivary)ENSG00000174876100
AMY1A / P04745 / amylase, alpha 1A (salivary)ENSG00000237763100
AMY2B / P19961 / amylase, alpha 2B (pancreatic)ENSG0000024003897
AMY2A / P04746 / amylase, alpha 2A (pancreatic)ENSG0000024348097


Protein motifs (from Interpro)
Interpro ID Name
 IPR006046  Alpha amylase
 IPR006047  Glycosyl hydrolase, family 13, catalytic domain
 IPR006048  Alpha-amylase/branching enzyme, C-terminal all beta
 IPR017853  Glycoside hydrolase superfamily
 IPR031319  Alpha-amylase, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004556 alpha-amylase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0043169 cation binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0103025 alpha-amylase activity (releasing maltohexaose) IEA


Pathways (from Reactome)
Pathway description
Digestion of dietary carbohydrate


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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