ENSG00000243480


Homo sapiens

Features
Gene ID: ENSG00000243480
  
Biological name :AMY2A
  
Synonyms : AMY2A / amylase, alpha 2A (pancreatic) / P04746
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p21.1
Gene start: 103616811
Gene end: 103625780
  
Corresponding Affymetrix probe sets: 208498_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000481450
Ensembl peptide - ENSP00000390832
Ensembl peptide - ENSP00000397582
NCBI entrez gene - 279     See in Manteia.
OMIM - 104650
RefSeq - NM_000699
RefSeq Peptide - NP_000690
swissprot - H7BZQ8
swissprot - P04746
Ensembl - ENSG00000243480
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 amy2aENSDARG00000013856Danio rerio
 zgc:66313ENSDARG00000030357Danio rerio
 zgc:92137ENSDARG00000009443Danio rerio
 AMY1AENSGALG00000005147Gallus gallus
 AMY2AENSGALG00000038740Gallus gallus
 Amy1ENSMUSG00000074264Mus musculus
 Amy2ENSMUSG00000074268Mus musculus
 Amy2a1ENSMUSG00000070360Mus musculus
 Amy2a2ENSMUSG00000096569Mus musculus
 Amy2a3ENSMUSG00000093931Mus musculus
 Amy2a4ENSMUSG00000096770Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AMY2B / P19961 / amylase, alpha 2B (pancreatic)ENSG0000024003899
AMY1C / P04745 / amylase, alpha 1C (salivary)ENSG0000018773397
AMY1A / P04745 / amylase, alpha 1A (salivary)ENSG0000023776397
AMY1B / P04745 / amylase, alpha 1B (salivary)ENSG0000017487697


Protein motifs (from Interpro)
Interpro ID Name
 IPR006046  Alpha amylase
 IPR006047  Glycosyl hydrolase, family 13, catalytic domain
 IPR006048  Alpha-amylase/branching enzyme, C-terminal all beta
 IPR017853  Glycoside hydrolase superfamily
 IPR031319  Alpha-amylase, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process NAS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016052 carbohydrate catabolic process IDA
 biological_processGO:0044245 polysaccharide digestion TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004556 alpha-amylase activity TAS
 molecular_functionGO:0005509 calcium ion binding IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0031404 chloride ion binding IDA
 molecular_functionGO:0043169 cation binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0103025 alpha-amylase activity (releasing maltohexaose) IEA


Pathways (from Reactome)
Pathway description
Digestion of dietary carbohydrate


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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