ENSMUSG00000074264


Mus musculus

Features
Gene ID: ENSMUSG00000074264
  
Biological name :Amy1
  
Synonyms : Alpha-amylase 1 / Amy1 / P00687
  
Possible biological names infered from orthology : AMY1A / AMY1B / AMY1C / AMY2A / AMY2B / amylase, alpha 1A (salivary) / amylase, alpha 1B (salivary) / amylase, alpha 1C (salivary) / amylase, alpha 2A (pancreatic) / amylase, alpha 2B (pancreatic) / P04745 / P04746 / P19961
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F3
Gene start: 113555710
Gene end: 113606699
  
Corresponding Affymetrix probe sets: 10501555 (MoGene1.0st)   1417765_a_at (Mouse Genome 430 2.0 Array)   1429504_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000070368
Ensembl peptide - ENSMUSP00000102150
Ensembl peptide - ENSMUSP00000120493
Ensembl peptide - ENSMUSP00000133875
NCBI entrez gene - 11722     See in Manteia.
MGI - MGI:88019
RefSeq - NM_007446
RefSeq - NM_001110505
RefSeq Peptide - NP_001103975
RefSeq Peptide - NP_031472
swissprot - P00687
swissprot - D3YYQ5
swissprot - G3UXY7
Ensembl - ENSMUSG00000074264
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 amy2aENSDARG00000013856Danio rerio
 zgc:66313ENSDARG00000030357Danio rerio
 zgc:92137ENSDARG00000009443Danio rerio
 AMY1AENSGALG00000005147Gallus gallus
 AMY2AENSGALG00000038740Gallus gallus
 AMY1AENSG00000237763Homo sapiens
 AMY1BENSG00000174876Homo sapiens
 AMY1CENSG00000187733Homo sapiens
 AMY2AENSG00000243480Homo sapiens
 AMY2BENSG00000240038Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P00688 / Amy2a2 / amylase 2a2 / AMY2A* / AMY1B* / AMY2B* / AMY1A* / AMY1C* / P19961* / P04745* / P04746* / amylase, alpha 1C (salivary)* / amylase, alpha 1B (salivary)* / amylase, alpha 1A ...ENSMUSG0000009656988
Amy2 / P00688 / Pancreatic alpha-amylase / AMY2B* / AMY1A* / AMY1B* / AMY1C* / AMY2A* / P19961* / P04745* / P04746* / amylase, alpha 1A (salivary)* / amylase, alpha 1C (salivary)* / amylas...ENSMUSG0000007426888
P00688 / Amy2a4 / amylase 2a4 / AMY2A* / AMY1B* / AMY2B* / AMY1A* / AMY1C* / P19961* / P04745* / P04746* / amylase, alpha 1C (salivary)* / amylase, alpha 1B (salivary)* / amylase, alpha 1A ...ENSMUSG0000009677088
P00688 / Amy2a3 / amylase 2a3 / AMY2A* / AMY1B* / AMY2B* / AMY1A* / AMY1C* / P19961* / P04745* / P04746* / amylase, alpha 1C (salivary)* / amylase, alpha 1B (salivary)* / amylase, alpha 1A ...ENSMUSG0000009393188
Amy2a1 / amylase 2a1 / AMY1C* / AMY2A* / AMY1B* / AMY2B* / AMY1A* / P19961* / P04745* / P04746* / amylase, alpha 1B (salivary)* / amylase, alpha 1A (salivary)* / amylase, alpha 1C (salivary...ENSMUSG0000007036042


Protein motifs (from Interpro)
Interpro ID Name
 IPR006046  Alpha amylase
 IPR006047  Glycosyl hydrolase, family 13, catalytic domain
 IPR006048  Alpha-amylase/branching enzyme, C-terminal all beta
 IPR017853  Glycoside hydrolase superfamily
 IPR031319  Alpha-amylase, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016052 carbohydrate catabolic process ISO
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space ISO
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004556 alpha-amylase activity ISO
 molecular_functionGO:0005509 calcium ion binding ISO
 molecular_functionGO:0016160 amylase activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0031404 chloride ion binding ISO
 molecular_functionGO:0043169 cation binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0103025 alpha-amylase activity (releasing maltohexaose) IEA


Pathways (from Reactome)
Pathway description
Digestion of dietary carbohydrate


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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