ENSG00000188290


Homo sapiens

Features
Gene ID: ENSG00000188290
  
Biological name :HES4
  
Synonyms : HES4 / hes family bHLH transcription factor 4 / Q9HCC6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.33
Gene start: 998962
Gene end: 1000172
  
Corresponding Affymetrix probe sets: 227347_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000304595
Ensembl peptide - ENSP00000425085
Ensembl peptide - ENSP00000393198
NCBI entrez gene - 57801     See in Manteia.
OMIM - 608060
RefSeq - XM_005244771
RefSeq - NM_001142467
RefSeq - NM_021170
RefSeq Peptide - NP_001135939
RefSeq Peptide - NP_066993
swissprot - E9PB28
swissprot - D6REB3
swissprot - Q9HCC6
Ensembl - ENSG00000188290
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 her9ENSDARG00000056438Danio rerio
 HES4ENSGALG00000002055Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HES1 / Q14469 / hes family bHLH transcription factor 1ENSG0000011431549
HES2 / Q9Y543 / hes family bHLH transcription factor 2ENSG0000006981232
HES6 / Q96HZ4 / hes family bHLH transcription factor 6ENSG0000014448523


Protein motifs (from Interpro)
Interpro ID Name
 IPR003650  Orange domain
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0030154 cell differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0008134 transcription factor binding NAS
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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