ENSG00000196154


Homo sapiens

Features
Gene ID: ENSG00000196154
  
Biological name :S100A4
  
Synonyms : P26447 / S100A4 / S100 calcium binding protein A4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q21.3
Gene start: 153543613
Gene end: 153550136
  
Corresponding Affymetrix probe sets: 203186_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357705
Ensembl peptide - ENSP00000346294
Ensembl peptide - ENSP00000357703
Ensembl peptide - ENSP00000357704
NCBI entrez gene - 6275     See in Manteia.
OMIM - 114210
RefSeq - NM_002961
RefSeq - NM_019554
RefSeq Peptide - NP_002952
RefSeq Peptide - NP_062427
swissprot - P26447
Ensembl - ENSG00000196154
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 icnENSDARG00000009978Danio rerio
 icn2ENSDARG00000055514Danio rerio
 s100sENSDARG00000036773Danio rerio
 s100tENSDARG00000055589Danio rerio
 ENSGALG00000037599Gallus gallus
 ENSGALG00000026613Gallus gallus
 P07091ENSMUSG00000001020Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P29034 / S100A2 / S100 calcium binding protein A2ENSG0000019675458
P33763 / S100A5 / S100 calcium binding protein A5ENSG0000019642048
P06703 / S100A6 / S100 calcium binding protein A6ENSG0000019795646
P23297 / S100A1 / S100 calcium binding protein A1ENSG0000016067846
P33764 / S100A3 / S100 calcium binding protein A3ENSG0000018801545
S100Z / Q8WXG8 / S100 calcium binding protein ZENSG0000017164344
S100B / P04271 / S100 calcium binding protein BENSG0000016030741
S100P / P25815 / S100 calcium binding protein PENSG0000016399338
P60903 / S100A10 / S100 calcium binding protein A10ENSG0000019774734
P31949 / S100A11 / S100 calcium binding protein A11ENSG0000016319128


Protein motifs (from Interpro)
Interpro ID Name
 IPR001751  S100/Calbindin-D9k, conserved site
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR013787  S100/CaBP-9k-type, calcium binding, subdomain
 IPR018247  EF-Hand 1, calcium-binding site
 IPR034325  S-100


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001837 epithelial to mesenchymal transition TAS
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IDA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005509 calcium ion binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046914 transition metal ion binding IEA
 molecular_functionGO:0048306 calcium-dependent protein binding IEA
 molecular_functionGO:0050786 RAGE receptor binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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