ENSG00000160678


Homo sapiens

Features
Gene ID: ENSG00000160678
  
Biological name :S100A1
  
Synonyms : P23297 / S100A1 / S100 calcium binding protein A1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q21.3
Gene start: 153627926
Gene end: 153632039
  
Corresponding Affymetrix probe sets: 205334_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357687
Ensembl peptide - ENSP00000389708
Ensembl peptide - ENSP00000292169
Ensembl peptide - ENSP00000357685
NCBI entrez gene - 6271     See in Manteia.
OMIM - 176940
RefSeq - NM_006271
RefSeq Peptide - NP_006262
swissprot - Q5T7Y4
swissprot - Q5T7Y5
swissprot - Q5T7Y6
swissprot - P23297
swissprot - A0A0S2Z4H2
Ensembl - ENSG00000160678
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 S100A1ENSGALG00000034458Gallus gallus
 S100a1ENSMUSG00000044080Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
S100B / P04271 / S100 calcium binding protein BENSG0000016030757
S100Z / Q8WXG8 / S100 calcium binding protein ZENSG0000017164357
S100P / P25815 / S100 calcium binding protein PENSG0000016399352
P29034 / S100A2 / S100 calcium binding protein A2ENSG0000019675450
P26447 / S100A4 / S100 calcium binding protein A4ENSG0000019615449
P60903 / S100A10 / S100 calcium binding protein A10ENSG0000019774747
P33763 / S100A5 / S100 calcium binding protein A5ENSG0000019642045
P06703 / S100A6 / S100 calcium binding protein A6ENSG0000019795641
P33764 / S100A3 / S100 calcium binding protein A3ENSG0000018801540
P31949 / S100A11 / S100 calcium binding protein A11ENSG0000016319140


Protein motifs (from Interpro)
Interpro ID Name
 IPR001751  S100/Calbindin-D9k, conserved site
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR013787  S100/CaBP-9k-type, calcium binding, subdomain
 IPR018247  EF-Hand 1, calcium-binding site
 IPR028486  Protein S100-A1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0002224 toll-like receptor signaling pathway TAS
 biological_processGO:0008016 regulation of heart contraction IEA
 biological_processGO:0021762 substantia nigra development HEP
 biological_processGO:0035556 intracellular signal transduction NAS
 biological_processGO:0051000 positive regulation of nitric-oxide synthase activity IDA
 biological_processGO:1901387 positive regulation of voltage-gated calcium channel activity IEA
 biological_processGO:1903672 positive regulation of sprouting angiogenesis IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016529 sarcoplasmic reticulum IDA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0031430 M band IEA
 cellular_componentGO:0031672 A band IEA
 cellular_componentGO:0031674 I band IEA
 cellular_componentGO:0032991 protein-containing complex NAS
 cellular_componentGO:0043005 neuron projection IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0044548 S100 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048306 calcium-dependent protein binding IEA
 molecular_functionGO:0051117 ATPase binding IPI


Pathways (from Reactome)
Pathway description
Regulation of TLR by endogenous ligand


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000136869 TLR4 / O00206 / toll like receptor 4  / complex / reaction
 ENSG00000154589 LY96 / Q9Y6Y9 / lymphocyte antigen 96  / reaction / complex
 ENSG00000160678 P23297 / S100A1 / S100 calcium binding protein A1  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr