ENSG00000197956


Homo sapiens

Features
Gene ID: ENSG00000197956
  
Biological name :S100A6
  
Synonyms : P06703 / S100A6 / S100 calcium binding protein A6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q21.3
Gene start: 153534599
Gene end: 153536244
  
Corresponding Affymetrix probe sets: 217728_at (Human Genome U133 Plus 2.0 Array)   228923_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000473589
Ensembl peptide - ENSP00000357708
Ensembl peptide - ENSP00000357709
Ensembl peptide - ENSP00000473547
NCBI entrez gene - 6277     See in Manteia.
OMIM - 114110
RefSeq - NM_014624
RefSeq - XM_017002033
RefSeq Peptide - NP_055439
swissprot - P06703
swissprot - R4GN98
Ensembl - ENSG00000197956
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 icnENSDARG00000009978Danio rerio
 icn2ENSDARG00000055514Danio rerio
 s100sENSDARG00000036773Danio rerio
 s100tENSDARG00000055589Danio rerio
 Q98953ENSGALG00000041826Gallus gallus
 P14069ENSMUSG00000001025Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P33763 / S100A5 / S100 calcium binding protein A5ENSG0000019642051
P26447 / S100A4 / S100 calcium binding protein A4ENSG0000019615451
P29034 / S100A2 / S100 calcium binding protein A2ENSG0000019675448
P33764 / S100A3 / S100 calcium binding protein A3ENSG0000018801546
P23297 / S100A1 / S100 calcium binding protein A1ENSG0000016067843
S100B / P04271 / S100 calcium binding protein BENSG0000016030739
S100Z / Q8WXG8 / S100 calcium binding protein ZENSG0000017164338
S100P / P25815 / S100 calcium binding protein PENSG0000016399334
P31949 / S100A11 / S100 calcium binding protein A11ENSG0000016319129
P60903 / S100A10 / S100 calcium binding protein A10ENSG0000019774727


Protein motifs (from Interpro)
Interpro ID Name
 IPR001751  S100/Calbindin-D9k, conserved site
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR013787  S100/CaBP-9k-type, calcium binding, subdomain
 IPR018247  EF-Hand 1, calcium-binding site
 IPR034118  Protein S100-A6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007409 axonogenesis NAS
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0048146 positive regulation of fibroblast proliferation NAS
 cellular_componentGO:0001726 ruffle IDA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope NAS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005523 tropomyosin binding IDA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0015075 ion transmembrane transporter activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0044548 S100 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048306 calcium-dependent protein binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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