Manteia

ENSMUSG00000001025

Mus musculus

Features

Gene ID:	ENSMUSG00000001025

Biological name :	S100a6

Synonyms :	P14069 / S100a6 / S100 calcium binding protein A6 (calcyclin)

Possible biological names infered from orthology :	P06703 / S100 calcium binding protein A6

Species:	Mus musculus

Chr. number:	3
Strand:	1
Band:	F1
Gene start:	90612882
Gene end:	90624181

Corresponding Affymetrix probe sets:	10493820 (MoGene1.0st) 1421375_a_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000001051 Ensembl peptide - ENSMUSP00000143111 Ensembl peptide - ENSMUSP00000143720 NCBI entrez gene - 20200 See in Manteia. MGI - MGI:1339467 RefSeq - NM_011313 RefSeq Peptide - NP_035443 swissprot - P14069 swissprot - Q545I9 Ensembl - ENSMUSG00000001025

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
P63084 / S100a5 / S100 calcium binding protein A5 / P33763*	ENSMUSG00000001023	49
P07091 / S100a4 / S100 calcium binding protein A4 / P26447*	ENSMUSG00000001020	49
P62818 / S100a3 / S100 calcium binding protein A3	ENSMUSG00000001021	44
S100a1 / S100 calcium binding protein A1 / P23297*	ENSMUSG00000044080	43
S100z / S100 calcium binding protein, zeta / Q8WXG8* / S100 calcium binding protein Z*	ENSMUSG00000021679	40
S100b / P50114 / S100 protein, beta polypeptide, neural / P04271* / S100 calcium binding protein B*	ENSMUSG00000033208	38
P50543 / S100a11 / Protein S100-A11 / P31949* / S100 calcium binding protein A11*	ENSMUSG00000027907	33
P08207 / S100a10 / S100 calcium binding protein A10 (calpactin) / P60903* / S100 calcium binding protein A10*	ENSMUSG00000041959	25
Gm42674 / P33764* / S100A3* / S100 calcium binding protein A3*	ENSMUSG00000105518	21

Protein motifs (from Interpro)

Interpro ID	Name
IPR001751	S100/Calbindin-D9k, conserved site
IPR002048	EF-hand domain
IPR011992	EF-hand domain pair
IPR013787	S100/CaBP-9k-type, calcium binding, subdomain
IPR018247	EF-Hand 1, calcium-binding site
IPR034118	Protein S100-A6

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0034220	ion transmembrane transport	IEA
cellular_component	GO:0001726	ruffle	ISO
cellular_component	GO:0005576	extracellular region	ISO
cellular_component	GO:0005634	nucleus	ISO
cellular_component	GO:0005635	nuclear envelope	IEA
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005829	cytosol	ISS
cellular_component	GO:0005886	plasma membrane	ISO
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	ISO
cellular_component	GO:0048471	perinuclear region of cytoplasm	ISO
molecular_function	GO:0005509	calcium ion binding	ISS
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0005523	tropomyosin binding	ISO
molecular_function	GO:0008270	zinc ion binding	IDA
molecular_function	GO:0015075	ion transmembrane transporter activity	IEA
molecular_function	GO:0042803	protein homodimerization activity	ISO
molecular_function	GO:0044548	S100 protein binding	ISO
molecular_function	GO:0046872	metal ion binding	IEA
molecular_function	GO:0048306	calcium-dependent protein binding	ISO

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0002997	enlarged seminal gland	"increased size, compared to the norm, of one of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens" [ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator]	Show Allelic Composition: Gtpbp2^{tm1b(KOMP)Mbp}/Gtpbp2⁺ Genetic Background: C57BL/6N-Gtpbp2^{tm1b(KOMP)Mbp}/Ucd
MP:0010378	increased respiratory quotient	"increase in the ratio of the volume of carbon dioxide released to oxygen consumed by a body tissue or an organism compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Gtpbp2^{tm1b(KOMP)Mbp}/Gtpbp2⁺ Genetic Background: C57BL/6N-Gtpbp2^{tm1b(KOMP)Mbp}/Ucd
MP:0011110	partial preweaning lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Rad9a^{tm1.1(KOMP)Wtsi}/Rad9a^{tm1.1(KOMP)Wtsi} Genetic Background: C57BL/6N-Rad9a^{tm1.1(KOMP)Wtsi}/Bay

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr