ENSG00000197747


Homo sapiens

Features
Gene ID: ENSG00000197747
  
Biological name :S100A10
  
Synonyms : P60903 / S100A10 / S100 calcium binding protein A10
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q21.3
Gene start: 151982915
Gene end: 151994390
  
Corresponding Affymetrix probe sets: 200872_at (Human Genome U133 Plus 2.0 Array)   238909_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357801
Ensembl peptide - ENSP00000357799
NCBI entrez gene - 6281     See in Manteia.
OMIM - 114085
RefSeq - NM_002966
RefSeq Peptide - NP_002957
swissprot - P60903
Ensembl - ENSG00000197747
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 s100a10aENSDARG00000037425Danio rerio
 s100a10bENSDARG00000025254Danio rerio
 P27003ENSGALG00000028774Gallus gallus
 P08207ENSMUSG00000041959Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P23297 / S100A1 / S100 calcium binding protein A1ENSG0000016067845
S100Z / Q8WXG8 / S100 calcium binding protein ZENSG0000017164343
S100P / P25815 / S100 calcium binding protein PENSG0000016399342
P31949 / S100A11 / S100 calcium binding protein A11ENSG0000016319137
S100B / P04271 / S100 calcium binding protein BENSG0000016030735
P26447 / S100A4 / S100 calcium binding protein A4ENSG0000019615435
P29034 / S100A2 / S100 calcium binding protein A2ENSG0000019675434
P33763 / S100A5 / S100 calcium binding protein A5ENSG0000019642031
P33764 / S100A3 / S100 calcium binding protein A3ENSG0000018801527
P06703 / S100A6 / S100 calcium binding protein A6ENSG0000019795625


Protein motifs (from Interpro)
Interpro ID Name
 IPR001751  S100/Calbindin-D9k, conserved site
 IPR011992  EF-hand domain pair
 IPR013787  S100/CaBP-9k-type, calcium binding, subdomain
 IPR028476  Protein S100-A10


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001765 membrane raft assembly IDA
 biological_processGO:0006900 vesicle budding from membrane IDA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0043547 positive regulation of GTPase activity IMP
 biological_processGO:0051099 positive regulation of binding IEA
 biological_processGO:0051290 protein heterotetramerization IDA
 biological_processGO:0051496 positive regulation of stress fiber assembly IMP
 biological_processGO:0051894 positive regulation of focal adhesion assembly IMP
 biological_processGO:0072659 protein localization to plasma membrane IDA
 biological_processGO:1900026 positive regulation of substrate adhesion-dependent cell spreading IMP
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0019897 extrinsic component of plasma membrane IEA
 cellular_componentGO:0045121 membrane raft IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0044325 ion channel binding IPI


Pathways (from Reactome)
Pathway description
Dissolution of Fibrin Clot


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000182718 ANXA2 / P07355 / annexin A2  / complex
 ENSG00000197747 P60903 / S100A10 / S100 calcium binding protein A10  / complex






 

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