ENSG00000196344


Homo sapiens

Features
Gene ID: ENSG00000196344
  
Biological name :ADH7
  
Synonyms : ADH7 / alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide / P40394
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q23
Gene start: 99412261
Gene end: 99435737
  
Corresponding Affymetrix probe sets: 210505_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000209665
Ensembl peptide - ENSP00000420613
Ensembl peptide - ENSP00000420300
Ensembl peptide - ENSP00000420269
Ensembl peptide - ENSP00000414254
NCBI entrez gene - 131     See in Manteia.
OMIM - 600086
RefSeq - NM_001166504
RefSeq - NM_000673
RefSeq Peptide - NP_000664
RefSeq Peptide - NP_001159976
swissprot - P40394
swissprot - C9JP14
swissprot - A0A0C4DG85
swissprot - E9PFG0
Ensembl - ENSG00000196344
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adh5ENSDARG00000080010Danio rerio
 adh8aENSDARG00000091211Danio rerio
 adh8bENSDARG00000024278Danio rerio
 zgc:63568ENSDARG00000087262Danio rerio
 zgc:77938ENSDARG00000088366Danio rerio
 ADH1CENSGALG00000030614Gallus gallus
 Adh7ENSMUSG00000055301Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADH1B / P00325 / alcohol dehydrogenase 1B (class I), beta polypeptideENSG0000019661665
ADH1C / P00326 / alcohol dehydrogenase 1C (class I), gamma polypeptideENSG0000024814465
ADH1A / P07327 / alcohol dehydrogenase 1A (class I), alpha polypeptideENSG0000018775864
ADH5 / P11766 / alcohol dehydrogenase 5 (class III), chi polypeptideENSG0000019789458
ADH6 / P28332 / alcohol dehydrogenase 6 (class V)ENSG0000017295557
ADH4 / P08319 / alcohol dehydrogenase 4 (class II), pi polypeptideENSG0000019809955


Protein motifs (from Interpro)
Interpro ID Name
 IPR002328  Alcohol dehydrogenase, zinc-type, conserved site
 IPR011032  GroES-like superfamily
 IPR013149  Alcohol dehydrogenase, C-terminal
 IPR013154  Alcohol dehydrogenase, N-terminal
 IPR028635  Alcohol dehydrogenase family, zinc-type, class-IV subfamily
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001523 retinoid metabolic process IDA
 biological_processGO:0006068 ethanol catabolic process IEA
 biological_processGO:0006069 ethanol oxidation TAS
 biological_processGO:0009617 response to bacterium IDA
 biological_processGO:0010430 fatty acid omega-oxidation IDA
 biological_processGO:0042572 retinol metabolic process IEA
 biological_processGO:0042573 retinoic acid metabolic process IEA
 biological_processGO:0045471 response to ethanol IDA
 biological_processGO:0055114 oxidation-reduction process IDA
 biological_processGO:1900116 extracellular negative regulation of signal transduction IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 molecular_functionGO:0004022 alcohol dehydrogenase (NAD) activity TAS
 molecular_functionGO:0004024 alcohol dehydrogenase activity, zinc-dependent IDA
 molecular_functionGO:0004031 aldehyde oxidase activity IDA
 molecular_functionGO:0004745 retinol dehydrogenase activity IDA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0019841 retinol binding IDA
 molecular_functionGO:0035276 ethanol binding IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048019 receptor antagonist activity IDA


Pathways (from Reactome)
Pathway description
Ethanol oxidation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000196344 ADH7 / P40394 / alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide  / complex






 

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