ENSDARG00000080010


Danio rerio

Features
Gene ID: ENSDARG00000080010
  
Biological name :adh5
  
Synonyms : adh5 / alcohol dehydrogenase 5
  
Possible biological names infered from orthology : Adh1 / ADH1A / ADH1B / ADH1C / ADH4 / ADH6 / Adh6a / Adh6b / ADH7 / Alcohol dehydrogenase 1 / alcohol dehydrogenase 1A (class I), alpha polypeptide / alcohol dehydrogenase 1B (class I), beta polypeptide / alcohol dehydrogenase 1C (class I), gamma polypeptide / Alcohol dehydrogenase 4 / alcohol dehydrogenase 4 (class II), pi polypeptide / alcohol dehydrogenase 5 (class III), chi polypeptide / alcohol dehydrogenase 6A (class V) / alcohol dehydrogenase 6B (class V) / alcohol dehydrogenase 6 (class V) / alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide / Alcohol dehydrogenase class-3 / Alcohol dehydrogenase class 4 mu/sigma chain / P00325 / P00326 / P00329 / P07327 / P08319 / P11766 / P28332 / P28474 / P40394 / Q64437 / Q9QYY9
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 43590816
Gene end: 43602968
  
Corresponding Affymetrix probe sets: Dr.1566.1.S1_at (Zebrafish Array)   NM_131849_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000099464
NCBI entrez gene - 116517     See in Manteia.
RefSeq - NM_131849
RefSeq Peptide - NP_571924
swissprot - Q6NXA6
ZFIN ID - ZDB-GENE-011003-1
Ensembl - ENSDARG00000080010
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ADH1CENSGALG00000030614Gallus gallus
 ADH5ENSGALG00000012245Gallus gallus
 ADH6ENSGALG00000020160Gallus gallus
 ADH1AENSG00000187758Homo sapiens
 ADH1BENSG00000196616Homo sapiens
 ADH1CENSG00000248144Homo sapiens
 ADH4ENSG00000198099Homo sapiens
 ADH5ENSG00000197894Homo sapiens
 ADH6ENSG00000172955Homo sapiens
 ADH7ENSG00000196344Homo sapiens
 Adh1ENSMUSG00000074207Mus musculus
 Adh4ENSMUSG00000037797Mus musculus
 Adh5ENSMUSG00000028138Mus musculus
 Adh6aENSMUSG00000053054Mus musculus
 Adh6bENSMUSG00000074206Mus musculus
 Adh7ENSMUSG00000055301Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zgc:77938 / Adh1* / ADH4* / ADH5* / ADH6* / ADH7* / ADH1B* / Adh6b* / ADH1A* / Adh6a* / ADH1C* / Q9QYY9* / P00325* / P00326* / P00329* / P07327* / P08319* / P11766* / P28332* / P28474* / P4...ENSDARG0000008836666
zgc:63568 / Adh1* / ADH4* / ADH5* / ADH6* / ADH7* / ADH1B* / Adh6b* / ADH1A* / Adh6a* / ADH1C* / Q9QYY9* / P00325* / P00326* / P00329* / P07327* / P08319* / P11766* / P28332* / P28474* / P4...ENSDARG0000008726265
adh8a / alcohol dehydrogenase 8a / ADH5* / ADH7* / ADH6* / Adh1* / ADH4* / ADH1A* / Adh6a* / Adh6b* / ADH1B* / ADH1C* / Q9QYY9* / P00325* / P00326* / P00329* / P07327* / P08319* / P11766* /...ENSDARG0000009121160
adh8b / alcohol dehydrogenase 8b / ADH5* / ADH7* / ADH6* / Adh1* / ADH4* / ADH1A* / Adh6a* / Adh6b* / ADH1B* / ADH1C* / Q9QYY9* / P00325* / P00326* / P00329* / P07327* / P08319* / P11766* /...ENSDARG0000002427856


Protein motifs (from Interpro)
Interpro ID Name
 IPR002328  Alcohol dehydrogenase, zinc-type, conserved site
 IPR011032  GroES-like superfamily
 IPR013149  Alcohol dehydrogenase, C-terminal
 IPR013154  Alcohol dehydrogenase, N-terminal
 IPR014183  Alcohol dehydrogenase class III
 IPR016040  NAD(P)-binding domain
 IPR020843  Polyketide synthase, enoylreductase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006069 ethanol oxidation IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051903 S-(hydroxymethyl)glutathione dehydrogenase activity IEA


Pathways (from Reactome)
Pathway description
Abacavir metabolism
RA biosynthesis pathway
Ethanol oxidation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000123 liver liver increased size , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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