ENSG00000198189


Homo sapiens

Features
Gene ID: ENSG00000198189
  
Biological name :HSD17B11
  
Synonyms : HSD17B11 / hydroxysteroid 17-beta dehydrogenase 11 / Q8NBQ5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q22.1
Gene start: 87336610
Gene end: 87391386
  
Corresponding Affymetrix probe sets: 217989_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000351035
Ensembl peptide - ENSP00000423775
NCBI entrez gene - 51170     See in Manteia.
OMIM - 612831
RefSeq - NM_016245
RefSeq Peptide - NP_057329
swissprot - D6RCD0
swissprot - Q8NBQ5
Ensembl - ENSG00000198189
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000010979Gallus gallus
 Q9EQ06ENSMUSG00000029311Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q7Z5P4 / HSD17B13 / hydroxysteroid 17-beta dehydrogenase 13ENSG0000017050964
RDH10 / Q8IZV5 / retinol dehydrogenase 10ENSG0000012103942
Q8N3Y7 / SDR16C5 / short chain dehydrogenase/reductase family 16C member 5ENSG0000017078642
DHRS3 / O75911 / dehydrogenase/reductase 3ENSG0000016249633


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006694 steroid biosynthetic process IEA
 biological_processGO:0006703 estrogen biosynthetic process TAS
 biological_processGO:0006710 androgen catabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005811 lipid droplet IDA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004303 estradiol 17-beta-dehydrogenase activity TAS
 molecular_functionGO:0016229 steroid dehydrogenase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Estrogen biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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