ENSG00000170786


Homo sapiens

Features
Gene ID: ENSG00000170786
  
Biological name :SDR16C5
  
Synonyms : Q8N3Y7 / SDR16C5 / short chain dehydrogenase/reductase family 16C member 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q12.1
Gene start: 56300010
Gene end: 56320776
  
Corresponding Affymetrix probe sets: 238017_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000307607
Ensembl peptide - ENSP00000379947
Ensembl peptide - ENSP00000431010
NCBI entrez gene - 195814     See in Manteia.
OMIM - 608989
RefSeq - XM_011517479
RefSeq - NM_001318049
RefSeq - NM_001318050
RefSeq - NM_138969
RefSeq Peptide - NP_001304978
RefSeq Peptide - NP_001304979
RefSeq Peptide - NP_620419
swissprot - Q8N3Y7
swissprot - G3V145
Ensembl - ENSG00000170786
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sdr16c5aENSDARG00000016233Danio rerio
 si:dkey-221h15.4ENSDARG00000041873Danio rerio
 SDR16C5ENSGALG00000015416Gallus gallus
 Q7TQA3ENSMUSG00000028236Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RDH10 / Q8IZV5 / retinol dehydrogenase 10ENSG0000012103942
Q8NBQ5 / HSD17B11 / hydroxysteroid 17-beta dehydrogenase 11ENSG0000019818939
Q7Z5P4 / HSD17B13 / hydroxysteroid 17-beta dehydrogenase 13ENSG0000017050937
DHRS3 / O75911 / dehydrogenase/reductase 3ENSG0000016249631


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0031065 positive regulation of histone deacetylation IDA
 biological_processGO:0035067 negative regulation of histone acetylation IDA
 biological_processGO:0042572 retinol metabolic process IEA
 biological_processGO:0042574 retinal metabolic process IDA
 biological_processGO:0043616 keratinocyte proliferation IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0000785 chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0017053 transcriptional repressor complex IDA
 molecular_functionGO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding IDA
 molecular_functionGO:0004745 retinol dehydrogenase activity TAS
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0033613 activating transcription factor binding IPI


Pathways (from Reactome)
Pathway description
RA biosynthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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