ENSMUSG00000028236


Mus musculus

Features
Gene ID: ENSMUSG00000028236
  
Biological name :Sdr16c5
  
Synonyms : Epidermal retinol dehydrogenase 2 / Q7TQA3 / Sdr16c5
  
Possible biological names infered from orthology : Q8N3Y7 / short chain dehydrogenase/reductase family 16C member 5
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: A1
Gene start: 3995936
Gene end: 4019663
  
Corresponding Affymetrix probe sets: 10511345 (MoGene1.0st)   1440523_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000046298
NCBI entrez gene - 242285     See in Manteia.
MGI - MGI:2668443
RefSeq - NM_181989
RefSeq Peptide - NP_871789
swissprot - Q7TQA3
Ensembl - ENSMUSG00000028236
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sdr16c5aENSDARG00000016233Danio rerio
 si:dkey-221h15.4ENSDARG00000041873Danio rerio
 SDR16C5ENSGALG00000015416Gallus gallus
 Q8N3Y7ENSG00000170786Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q05A13 / Sdr16c6 / Short-chain dehydrogenase/reductase family 16C member 6 ENSMUSG0000007101960
Rdh10 / Q8VCH7 / Retinol dehydrogenase 10 / Q8IZV5*ENSMUSG0000002592145
Q9EQ06 / Hsd17b11 / hydroxysteroid (17-beta) dehydrogenase 11 / Q8NBQ5*ENSMUSG0000002931142
Dhrs3 / O88876 / Short-chain dehydrogenase/reductase 3 / O75911* / dehydrogenase/reductase 3*ENSMUSG0000006602636
Q8VCR2 / Hsd17b13 / hydroxysteroid (17-beta) dehydrogenase 13 / Q7Z5P4*ENSMUSG0000003452836


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0031065 positive regulation of histone deacetylation ISO
 biological_processGO:0035067 negative regulation of histone acetylation ISO
 biological_processGO:0042572 retinol metabolic process IEA
 biological_processGO:0042574 retinal metabolic process ISO
 biological_processGO:0043616 keratinocyte proliferation ISO
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0000785 chromatin ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0017053 transcriptional repressor complex ISO
 molecular_functionGO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding ISO
 molecular_functionGO:0004745 retinol dehydrogenase activity IEA
 molecular_functionGO:0008134 transcription factor binding ISO
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0033613 activating transcription factor binding ISO


Pathways (from Reactome)
Pathway description
RA biosynthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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