ENSG00000162496


Homo sapiens

Features
Gene ID: ENSG00000162496
  
Biological name :DHRS3
  
Synonyms : dehydrogenase/reductase 3 / DHRS3 / O75911
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.21
Gene start: 12567910
Gene end: 12617731
  
Corresponding Affymetrix probe sets: 202481_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000480439
Ensembl peptide - ENSP00000387903
Ensembl peptide - ENSP00000478218
NCBI entrez gene - 9249     See in Manteia.
OMIM - 612830
RefSeq - XM_017002809
RefSeq - NM_001319225
RefSeq - NM_001324370
RefSeq - NM_004753
RefSeq - XM_006711036
RefSeq Peptide - NP_001311299
RefSeq Peptide - NP_004744
RefSeq Peptide - NP_001306154
swissprot - O75911
swissprot - Q5SUY4
swissprot - A0A087WTY3
Ensembl - ENSG00000162496
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dhrs3aENSDARG00000044982Danio rerio
 dhrs3bENSDARG00000044803Danio rerio
 DHRS3ENSGALG00000030376Gallus gallus
 Dhrs3ENSMUSG00000066026Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RDH10 / Q8IZV5 / retinol dehydrogenase 10ENSG0000012103936
Q8N3Y7 / SDR16C5 / short chain dehydrogenase/reductase family 16C member 5ENSG0000017078633
Q8NBQ5 / HSD17B11 / hydroxysteroid 17-beta dehydrogenase 11ENSG0000019818932
Q7Z5P4 / HSD17B13 / hydroxysteroid 17-beta dehydrogenase 13ENSG0000017050932


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR032969  Short-chain dehydrogenase/reductase 3
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001523 retinoid metabolic process IEA
 biological_processGO:0003151 outflow tract morphogenesis IEA
 biological_processGO:0007601 visual perception TAS
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0030278 regulation of ossification IEA
 biological_processGO:0042572 retinol metabolic process IEA
 biological_processGO:0048387 negative regulation of retinoic acid receptor signaling pathway IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060021 roof of mouth development IEA
 biological_processGO:0060349 bone morphogenesis IEA
 biological_processGO:0060411 cardiac septum morphogenesis IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042622 photoreceptor outer segment membrane TAS
 molecular_functionGO:0000166 nucleotide binding TAS
 molecular_functionGO:0004745 retinol dehydrogenase activity IEA
 molecular_functionGO:0009055 electron transfer activity TAS
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0052650 NADP-retinol dehydrogenase activity TAS


Pathways (from Reactome)
Pathway description
The retinoid cycle in cones (daylight vision)
RA biosynthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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