ENSG00000198492


Homo sapiens

Features
Gene ID: ENSG00000198492
  
Biological name :YTHDF2
  
Synonyms : Q9Y5A9 / YTHDF2 / YTH N6-methyladenosine RNA binding protein 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p35.3
Gene start: 28736621
Gene end: 28769775
  
Corresponding Affymetrix probe sets: 217812_at (Human Genome U133 Plus 2.0 Array)   222430_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000439394
Ensembl peptide - ENSP00000474446
Ensembl peptide - ENSP00000474784
Ensembl peptide - ENSP00000362918
Ensembl peptide - ENSP00000444660
NCBI entrez gene - 51441     See in Manteia.
OMIM - 610640
RefSeq - NM_001173128
RefSeq - NM_001172828
RefSeq - NM_016258
RefSeq Peptide - NP_001166299
RefSeq Peptide - NP_001166599
RefSeq Peptide - NP_057342
swissprot - Q9Y5A9
swissprot - S4R3J8
swissprot - S4R3V3
Ensembl - ENSG00000198492
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 E7F1H9ENSDARG00000014498Danio rerio
 YTHDF2ENSGALG00000034831Gallus gallus
 Q91YT7ENSMUSG00000040025Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q7Z739 / YTHDF3 / YTH N6-methyladenosine RNA binding protein 3ENSG0000018572865
Q9BYJ9 / YTHDF1 / YTH N6-methyladenosine RNA binding protein 1ENSG0000014965864


Protein motifs (from Interpro)
Interpro ID Name
 IPR007275  YTH domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001556 oocyte maturation ISS
 biological_processGO:0006959 humoral immune response TAS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0043488 regulation of mRNA stability IMP
 biological_processGO:0045746 negative regulation of Notch signaling pathway ISS
 biological_processGO:0048477 oogenesis IEA
 biological_processGO:0048598 embryonic morphogenesis ISS
 biological_processGO:0061157 mRNA destabilization IMP
 biological_processGO:0098508 endothelial to hematopoietic transition ISS
 biological_processGO:1902036 regulation of hematopoietic stem cell differentiation ISS
 biological_processGO:1903538 regulation of meiotic cell cycle process involved in oocyte maturation ISS
 biological_processGO:1903679 positive regulation of cap-independent translational initiation IDA
 cellular_componentGO:0000932 P-body IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:1990247 N6-methyladenosine-containing RNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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