ENSG00000198874


Homo sapiens

Features
Gene ID: ENSG00000198874
  
Biological name :TYW1
  
Synonyms : Q9NV66 / tRNA-yW synthesizing protein 1 homolog / TYW1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q11.21
Gene start: 66995173
Gene end: 67239519
  
Corresponding Affymetrix probe sets: 218347_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000352645
Ensembl peptide - ENSP00000478959
Ensembl peptide - ENSP00000398897
Ensembl peptide - ENSP00000354795
NCBI entrez gene - 55253     See in Manteia.
OMIM - 611243
RefSeq - XM_011516372
RefSeq - XM_017012392
RefSeq - NM_018264
RefSeq Peptide - NP_060734
swissprot - Q9NV66
swissprot - C9J9Q4
swissprot - A0A087WUV9
Ensembl - ENSG00000198874
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tyw1ENSDARG00000062987Danio rerio
 ENSGALG00000001110Gallus gallus
 Tyw1ENSMUSG00000056310Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TYW1B / tRNA-yW synthesizing protein 1 homolog BENSG0000027714987


Protein motifs (from Interpro)
Interpro ID Name
 IPR001094  Flavodoxin-like
 IPR007197  Radical SAM
 IPR008254  Flavodoxin/nitric oxide synthase
 IPR013785  Aldolase-type TIM barrel
 IPR013917  tRNA wybutosine-synthesis
 IPR029039  Flavoprotein-like superfamily
 IPR034556  S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0010181 FMN binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA
 molecular_functionGO:0102521 tRNA-4-demethylwyosine synthase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of wybutosine at G37 of tRNA(Phe)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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