ENSG00000204390


Homo sapiens

Features
Gene ID: ENSG00000204390
  
Biological name :HSPA1L
  
Synonyms : heat shock protein family A (Hsp70) member 1 like / HSPA1L / P34931
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.33
Gene start: 31809619
Gene end: 31815065
  
Corresponding Affymetrix probe sets: 210189_at (Human Genome U133 Plus 2.0 Array)   233694_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000364805
NCBI entrez gene - 3305     See in Manteia.
OMIM - 140559
RefSeq - NM_005527
RefSeq Peptide - NP_005518
swissprot - A0A1U9X7W7
swissprot - P34931
Ensembl - ENSG00000204390
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Hspa1lENSMUSG00000007033Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HSPA1B / P0DMV9 / heat shock protein family A (Hsp70) member 1BENSG0000020438889
HSPA1A / P0DMV8 / heat shock protein family A (Hsp70) member 1AENSG0000020438989
HSPA8 / P11142 / heat shock protein family A (Hsp70) member 8ENSG0000010997183
HSPA2 / P54652 / heat shock protein family A (Hsp70) member 2ENSG0000012680382
HSPA6 / P17066 / heat shock protein family A (Hsp70) member 6ENSG0000017311079
HSPA5 / P11021 / heat shock protein family A (Hsp70) member 5ENSG0000004457462
HSPA14 / Q0VDF9 / heat shock protein family A (Hsp70) member 14ENSG0000018752227
HSPA14 / heat shock protein family A (Hsp70) member 14ENSG000002840247


Protein motifs (from Interpro)
Interpro ID Name
 IPR013126  Heat shock protein 70 family
 IPR018181  Heat shock protein 70, conserved site
 IPR029047  Heat shock protein 70kD, peptide-binding domain superfamily
 IPR029048  Heat shock protein 70kD, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006986 response to unfolded protein TAS
 biological_processGO:0007339 binding of sperm to zona pellucida IEA
 biological_processGO:0042026 protein refolding IDA
 biological_processGO:1900034 regulation of cellular response to heat TAS
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IMP
 cellular_componentGO:0002199 zona pellucida receptor complex IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0008180 COP9 signalosome IDA
 cellular_componentGO:0044297 cell body IEA
 cellular_componentGO:0072562 blood microparticle HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0031072 heat shock protein binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0051082 unfolded protein binding IDA


Pathways (from Reactome)
Pathway description
Regulation of HSF1-mediated heat shock response
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Attenuation phase
HSF1-dependent transactivation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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