ENSG00000205302


Homo sapiens

Features
Gene ID: ENSG00000205302
  
Biological name :SNX2
  
Synonyms : O60749 / SNX2 / sorting nexin 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q23.2
Gene start: 122774996
Gene end: 122830108
  
Corresponding Affymetrix probe sets: 202113_s_at (Human Genome U133 Plus 2.0 Array)   202114_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000421663
Ensembl peptide - ENSP00000422560
Ensembl peptide - ENSP00000422413
Ensembl peptide - ENSP00000368831
NCBI entrez gene - 6643     See in Manteia.
OMIM - 605929
RefSeq - NM_003100
RefSeq - NM_001278199
RefSeq Peptide - NP_001265128
RefSeq Peptide - NP_003091
swissprot - O60749
swissprot - D6RC15
swissprot - D6RBT1
Ensembl - ENSG00000205302
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 snx2ENSDARG00000104128Danio rerio
 SNX2ENSGALG00000005337Gallus gallus
 Snx2ENSMUSG00000034484Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SNX1 / Q13596 / sorting nexin 1ENSG0000002852858
SNX5 / Q9Y5X3 / sorting nexin 5ENSG0000008900619
SNX32 / Q86XE0 / sorting nexin 32ENSG0000017280318
SNX6 / Q9UNH7 / sorting nexin 6ENSG0000012951518


Protein motifs (from Interpro)
Interpro ID Name
 IPR001683  Phox homologous domain
 IPR005329  Sorting nexin, N-terminal
 IPR015404  Sorting nexin Vps5-like, C-terminal
 IPR027267  AH/BAR domain superfamily
 IPR028653  Sorting nexin-2
 IPR036871  PX domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006897 endocytosis IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016050 vesicle organization IBA
 biological_processGO:0034498 early endosome to Golgi transport IBA
 biological_processGO:0042147 retrograde transport, endosome to Golgi NAS
 biological_processGO:0051259 protein complex oligomerization IDA
 biological_processGO:0072673 lamellipodium morphogenesis IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005764 lysosome IDA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0010008 endosome membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019898 extrinsic component of membrane IBA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030904 retromer complex IDA
 cellular_componentGO:0030905 retromer, tubulation complex NAS
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005154 epidermal growth factor receptor binding IDA
 molecular_functionGO:0005158 insulin receptor binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IBA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0046982 protein heterodimerization activity NAS
 molecular_functionGO:1990459 transferrin receptor binding IDA
 molecular_functionGO:1990460 leptin receptor binding IDA


Pathways (from Reactome)
Pathway description
Golgi Associated Vesicle Biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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