ENSG00000028528


Homo sapiens

Features
Gene ID: ENSG00000028528
  
Biological name :SNX1
  
Synonyms : Q13596 / SNX1 / sorting nexin 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q22.31
Gene start: 64094123
Gene end: 64146090
  
Corresponding Affymetrix probe sets: 201716_at (Human Genome U133 Plus 2.0 Array)   213364_s_at (Human Genome U133 Plus 2.0 Array)   214531_s_at (Human Genome U133 Plus 2.0 Array)   216357_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000486714
Ensembl peptide - ENSP00000453567
Ensembl peptide - ENSP00000453785
Ensembl peptide - ENSP00000261889
Ensembl peptide - ENSP00000369638
Ensembl peptide - ENSP00000452651
Ensembl peptide - ENSP00000452652
Ensembl peptide - ENSP00000452668
Ensembl peptide - ENSP00000452759
Ensembl peptide - ENSP00000452852
Ensembl peptide - ENSP00000452931
NCBI entrez gene - 6642     See in Manteia.
OMIM - 601272
RefSeq - XM_005254611
RefSeq - NM_001242933
RefSeq - NM_003099
RefSeq - NM_148955
RefSeq Peptide - NP_683758
RefSeq Peptide - NP_001229862
RefSeq Peptide - NP_003090
swissprot - Q13596
swissprot - H0YK42
swissprot - H0YK43
swissprot - H0YK58
swissprot - H0YKL5
swissprot - H0YKD5
swissprot - H0YKT3
swissprot - J3KPH4
Ensembl - ENSG00000028528
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 snx1aENSDARG00000071031Danio rerio
 SNX1ENSGALG00000002189Gallus gallus
 Snx1ENSMUSG00000032382Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SNX2 / O60749 / sorting nexin 2ENSG0000020530254
SNX5 / Q9Y5X3 / sorting nexin 5ENSG0000008900616
SNX32 / Q86XE0 / sorting nexin 32ENSG0000017280316
SNX6 / Q9UNH7 / sorting nexin 6ENSG0000012951515


Protein motifs (from Interpro)
Interpro ID Name
 IPR001683  Phox homologous domain
 IPR005329  Sorting nexin, N-terminal
 IPR015404  Sorting nexin Vps5-like, C-terminal
 IPR027267  AH/BAR domain superfamily
 IPR028660  Sorting nexin-1
 IPR034901  Sorting Nexin 1, PX domain
 IPR036871  PX domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016050 vesicle organization IBA
 biological_processGO:0016197 endosomal transport IEA
 biological_processGO:0031623 receptor internalization IMP
 biological_processGO:0034498 early endosome to Golgi transport IMP
 biological_processGO:0042147 retrograde transport, endosome to Golgi IEA
 biological_processGO:0045732 positive regulation of protein catabolic process IEA
 biological_processGO:0072673 lamellipodium morphogenesis IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005764 lysosome IDA
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019898 extrinsic component of membrane IBA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030904 retromer complex IEA
 cellular_componentGO:0030905 retromer, tubulation complex NAS
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0031982 vesicle IDA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0005154 epidermal growth factor receptor binding IDA
 molecular_functionGO:0005158 insulin receptor binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0046982 protein heterodimerization activity NAS
 molecular_functionGO:1990459 transferrin receptor binding IDA
 molecular_functionGO:1990460 leptin receptor binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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