ENSG00000129515


Homo sapiens

Features
Gene ID: ENSG00000129515
  
Biological name :SNX6
  
Synonyms : Q9UNH7 / SNX6 / sorting nexin 6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q13.1
Gene start: 34561094
Gene end: 34630183
  
Corresponding Affymetrix probe sets: 217789_at (Human Genome U133 Plus 2.0 Array)   222410_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000452520
Ensembl peptide - ENSP00000452231
Ensembl peptide - ENSP00000452577
Ensembl peptide - ENSP00000355217
Ensembl peptide - ENSP00000379779
Ensembl peptide - ENSP00000450863
Ensembl peptide - ENSP00000451415
Ensembl peptide - ENSP00000452082
NCBI entrez gene - 58533     See in Manteia.
OMIM - 606098
RefSeq - XM_006720224
RefSeq - NM_021249
RefSeq - NM_152233
RefSeq Peptide - NP_067072
RefSeq Peptide - NP_689419
swissprot - G3V5X9
swissprot - H0YJF8
swissprot - Q9UNH7
swissprot - A0A0A0MRI2
swissprot - G3V2U1
swissprot - G3V589
swissprot - G3V4Z5
swissprot - G3V5U2
Ensembl - ENSG00000129515
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 snx6ENSDARG00000058444Danio rerio
 SNX6ENSGALG00000010025Gallus gallus
 Snx6ENSMUSG00000005656Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SNX32 / Q86XE0 / sorting nexin 32ENSG0000017280366
SNX5 / Q9Y5X3 / sorting nexin 5ENSG0000008900662
SNX2 / O60749 / sorting nexin 2ENSG0000020530223
SNX1 / Q13596 / sorting nexin 1ENSG0000002852821


Protein motifs (from Interpro)
Interpro ID Name
 IPR001683  Phox homologous domain
 IPR014637  Sorting nexin-5/6/32
 IPR015404  Sorting nexin Vps5-like, C-terminal
 IPR027267  AH/BAR domain superfamily
 IPR028657  Sorting nexin-6
 IPR036871  PX domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006897 endocytosis IBA
 biological_processGO:0007175 negative regulation of epidermal growth factor-activated receptor activity NAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016050 vesicle organization IBA
 biological_processGO:0016241 regulation of macroautophagy NAS
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IDA
 biological_processGO:0042147 retrograde transport, endosome to Golgi NAS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IDA
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019898 extrinsic component of membrane IBA
 cellular_componentGO:0030904 retromer complex IDA
 cellular_componentGO:0030905 retromer, tubulation complex NAS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0097422 tubular endosome IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0034452 dynactin binding IDA
 molecular_functionGO:0034713 type I transforming growth factor beta receptor binding IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0046982 protein heterodimerization activity NAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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