ENSG00000213719


Homo sapiens

Features
Gene ID: ENSG00000213719
  
Biological name :CLIC1
  
Synonyms : chloride intracellular channel 1 / CLIC1 / O00299
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.33
Gene start: 31730581
Gene end: 31739763
  
Corresponding Affymetrix probe sets: 208659_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000364935
Ensembl peptide - ENSP00000379229
Ensembl peptide - ENSP00000479808
Ensembl peptide - ENSP00000364934
Ensembl peptide - ENSP00000364940
NCBI entrez gene - 1192     See in Manteia.
OMIM - 602872
RefSeq - NM_001287593
RefSeq - NM_001287594
RefSeq - NM_001288
RefSeq Peptide - NP_001274522
RefSeq Peptide - NP_001274523
RefSeq Peptide - NP_001279
swissprot - O00299
swissprot - Q5SRT3
Ensembl - ENSG00000213719
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 clic1ENSDARG00000103340Danio rerio
 Clic1ENSMUSG00000007041Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CLIC4 / Q9Y696 / chloride intracellular channel 4ENSG0000016950467
CLIC6 / Q96NY7 / chloride intracellular channel 6ENSG0000015921265
CLIC5 / Q9NZA1 / chloride intracellular channel 5ENSG0000011278263
CLIC2 / O15247 / chloride intracellular channel 2ENSG0000015596261
CLIC3 / O95833 / chloride intracellular channel 3ENSG0000016958351


Protein motifs (from Interpro)
Interpro ID Name
 IPR002946  Intracellular chloride channel
 IPR004045  Glutathione S-transferase, N-terminal
 IPR010987  Glutathione S-transferase, C-terminal-like
 IPR030259  Chloride intracellular channel protein 1
 IPR036249  Thioredoxin-like superfamily
 IPR036282  Glutathione S-transferase, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006821 chloride transport IDA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0045669 positive regulation of osteoblast differentiation IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0051881 regulation of mitochondrial membrane potential IEA
 biological_processGO:0070527 platelet aggregation HMP
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005635 nuclear envelope IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005903 brush border TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0031982 vesicle HDA
 cellular_componentGO:0034707 chloride channel complex IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0070062 extracellular exosome IDA
 cellular_componentGO:0072562 blood microparticle HDA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005254 chloride channel activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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